Abstract
The influence of any treatment on development of atherosclerosis can be assayed directly in animals by obtaining autopsy data after a suitable experimental period. In man the determination of atherosclerotic involvement is indirect and depends upon measurements of serum or plasma lipid or lipoprotein components. Elevated plasma total cholesterol or low-density lipoprotein (LDL) levels are generally agreed to be positively correlated with the risk of developing cardiovascular disease (Kagan et al., 1962; Gordon et al., 1974). Elevated levels of high-density lipoprotein (HDL), HDL-choles-terol, or ratio of HDL- to LDL-cholesterol are assumed to be negatively correlated (Barr et al., 1951; Miller and Miller, 1975). Thus, in man alteration of risk may be adduced to follow changes in levels of any of these parameters.
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References
Anderson, J. W., 1982, Dietary fiber and diabetes, in: Dietary Fiber in Health and Disease ( G. V. Vahouny and D. Kritchevsky, eds.), Plenum, New York, pp. 151–167.
Barr, D. P., Russ, E. M., and Eder, H. A., 1951, Protein-lipid relationships in human plasma. II. Atherosclerosis and related conditions, Am. J. Med. 11: 480–493.
Berenson, L. M., Bhandaru, R., R., Radhakrishnamurthy, B., Srinivasan, S. B., and Berenson, G. S., 1975, The effect of dietary pectin on serum lipoprotein cholesterol in rabbits, Life Sci. 16: 1533–1544.
Burr, M. L., and Sweetnam, P. M., 1982, Vegetarianism, dietary fiber and mortality, Am. J. Clin. Nutr. 36: 873–877.
Burselm, J., Schonfeld, G., Howard, M. A., Werdman, S. W., and Miller, J. P., 1978, Plasma apoprotein and lipoprotein lipid levels in vegetarians, Metabolism 27: 711–719.
Chen, W. L., and Anderson, J. W., 1979, Effects of plant fiber in decreasing plasma total cholesterol and increasing high-density lipoprotein cholesterol, Proc. Soc. Exp. Biol. Med. 162: 310–313.
Fisher, H., Soller, W. G., and Griminger, P., 1966, The retardation by pectin of cholesterol- induced atherosclerosis in fowl, J. Atheroscler. Res. 6: 292–298.
Gordon, T., Garcia-Palmieri, M. R., Kagan, A., Kannel, W. B., and Schiffman, J., 1974, Differences in coronary heart disease in Framingham, Honolulu and Puerto Rico, J. Chronic Dis. 27: 329–344.
Grande, F., 1974, Sugars in cardiovascular disease, in: Sugars in Nutrition ( H. I. Sipple and K. W. McNutt, eds.), Academic, New York, pp. 401–437.
Hardinge, M. G., Chambers, A. C., Crooks, H., and Stare, F. J., 1958, Nutritional studies of vegetarians, Am. J. Clin. Nutr. 6: 523–525.
Hirsch, E. F., and Nailor, R., 1955, Atherosclerosis. III. Fractional distribution of the esterified fatty acids of the blood lipids of rabbits with cream and cholesterol diets, Arch. Pathol. 59: 419–428.
Howard, A. N., Gresham, G. A., Jennings, I. W., and Jones, D., 1967, The effect of drugs on hypercholesterolemia and atherosclerosis induced by semi-synthetic, low cholesterol diets, Prog. Biochem. Pharmacol. 2: 117–127.
Jenkins, D. J. A., Reynolds, D., Slavin, B., Leeds, A. R., Jenkins, A. L., and Jepson, E. M., 1980, Dietary fiber and blood lipids: Treatment of hypercholesterolemia with guar crisp-bread, Am. J. Clin. Nutr. 33: 575–581.
Kagan, A., Kannel, W. B., Dawber, T. R., and Revotskie, N., 1962, The coronary profile, Ann. N. Y. Acad. Sci. 97: 883–894.
Kay, R. M., 1980, Effects of dietary fibre on serum lipid levels and fecal bile acid excretion, Can. Med. Assoc. J. 123: 1213–1217.
Kay, R. M., and Truswell, A. S., 1980, Dietary fiber: Effects on plasma and biliary lipids in man, in: Medical Aspects of Dietary Fiber ( G. A. Spiller and R. M. Kay, eds.), Plenum, New York, pp 153–173.
Kelsay, J. L., 1978, A review of research on effects of fiber intake on man, Am. J. Clin. Nutr. 31: 142–159.
Kirby, R. W., Anderson, J. W., Sieling, B., Rees, E. D., Chen, W. J., Miller, R. E., and Kay, R. M., 1981, Oat bran intake selectively lowers serum low density lipoprotein cholesterol concentrations of hypercholesterolemic men, Am. J. Clin. Nutr. 34: 824–829.
Kiriyama, S., Okozaki, Y., and Yoshida, A., 1969, Hypocholesterolemic effect of polysaccharides and polysaccharide-rich foodstuffs in cholesterolfed rats, J. Nutr. 97: 382–388.
Knuiman, J. T., and West, C. E., 1982, The concentration of cholesterol in serum and in various serum lipoproteins in macrobiotic, vegetarian and non-vegetarian men and boys, Atherosclerosis 43: 71–82.
Kritchevsky, D., 1964, Experimental atherosclerosis in rabbits fed cholesterol-free diets, J. Ath- eroscler. Res. 4: 103–105.
Kritchevsky, D., and Tepper, S. A., 1965, Factors affecting atherosclerosis in rabbits fed cholesterol-free diets, Life Sci. 4: 1467–1471.
Kritchevsky, D., and Tepper, S. A., 1968, Experimental and atherosclerosis in rabbits fed cholesterol-free diets: Influence of chow components, Atheroscler. Res 8: 357–369.
Kritchevsky, D., Moyer, A. W., Tesar, W. C., Logan, J. B., Brown, R, A., Davies, M. C., and Cox, H. R., 1954, Effect of cholesterol vehicle in experimental atherosclerosis, Am. J. Physiol. 178: 30–32
Kritchevsky, D., Davidson, L. M., Shapiro, I. L., Kim, H. K., Kitagawa, M., Malhotra, S., Nair P. P., Clarkson, T. B., Bersohn, I., and Winter, P. A. D., 1974, Lipid metabolism and experimental atherosclerosis in baboons: Influence of cholesterol-free, semi-synthetic diets, Am. J. Clin. Nutr. 27: 29–50.
Kritchevsky, D., Tepper, S. A., Kim, H. K., Moses, D. E., and Story, J. A., 1975a, Experimental atherosclerosis in rabbits fed cholesterol-free diets. 4. Investigation into the source of cholesteremia, Exp. Mol. Pathol. 22: 11–19.
Kritchevsky, D., Tepper, S. A., and Story, J. A., 1975b, Non-nutritive fiber and lipid metabolism, J. Food Sci. 40: 8–11.
Kritchevsky, D., Tepper, S. A., Williams, D. E., and Story, J. A., 1977, Experimental atherosclerosis in rabbits fed cholesterol-free diets. 7. Interaction of animal or vegetable protein with fiber, Atherosclerosis 26: 397–403.
Kritchevsky, D., Davidson, L. M., Krendel, D. A., Van der Watt, J. J., Russell, D., Friedland, S., and Mendelsohn, D., 1981, Influence of dietary fiber on aortic sudanophilia in vervet monkeys, Ann. Nutr. Metab. 25: 125–136.
Kritchevsky, D., Tepper, S. A., and Goodman, G., 1985, Diet, nutrient intake and metabolism in populations at high and low risk for colon cancer. 7. Relation of diet to serum lipids, Am. J. Clin. Nutr., 40: 921–926.
Lambert, G. F., Miller, J. P., Olsen, R. T., and Frost, D. V., 1958, Hypercholesteremia and atherosclerosis induced in rabbits by purified high fat rations devoid of cholesterol, Proc. Soc. Exp. Biol. Med. 97: 544–549.
Malinow, M. R., McLaughlin, P., Naito, H. K., Lewis, L. A., and McNulty, W. P., 1978, Effect of alfalfa meal on shrinkage (regression) of atherosclerotic plaques during cholesterol feeding in monkeys, Atherosclerosis 30: 27–43.
Malmros, H., and Wigand, G., 1959, Atherosclerosis and deficiency of essential fatty acids, Lancet 2: 749–751.
Miller, G. J., and Miller, N. E., 1975, Plasma high density lipoprotein concentration and development of ischaemic heart disease, Lancet 1: 16–19.
Moore, J. H., 1967, The effect of the type of roughage in the diet on plasma cholesterol levels and aortic atherosis in rabbits, Br. J. Nutr. 21: 207–215.
Nakamura, H., Ishikawa, T., Toda, N., Kagami, A., Kondo, K., Myazima, E., and Takeyama, S., 1982, Effect of several kinds of dietary fibres on serum and lipoprotein lipids, Nutr. Rep. Int. 26: 215–221.
Sacks, F. M., Castelli, W. P., Donner, A., and Kass, E. H., 1975, Plasma lipids and lipoproteins in vegetarians and controls, N. Engl. J. Med. 292: 1148–1151.
Stasse-Wolthuis, M., Hautvast, J. G. A. J., Hermus, R. J. J., Katan, M. N., Bausch, J. E., Reitberg-Brussnard, J. H., Velma, J. P., Zondervan, J. G., Eastwood, M. A., and Brydon, G. R., 1979, The effect of a natural high fiber diet on serum lipids, fecal lipids and colonic function, Am. J. Clin. Nutr. 32: 1881–1888.
Stasse-Wolthuis, M., Albers, H. F. F., van Jeveren, J. G. C., Wil de Jong, J., Hautvast, J. G. A. J., Hermus, R. J. J., Katan, M. B., Brydon, G. B., and Eastwood, M. A., 1980, Influence of dietary fiber from vegetables and fruits, bran, citrus pectin on serum lipids, fecal lipids and colonic functions, Am. J. Clin. Nutr. 33: 1745–1756.
Steiner, A., Varsos, A., and Samuel, P., 1959, Effect of saturated and unsaturated fats on the concentration of serum cholesterol and experimental atherosclerosis, Circ. Res. 7: 448–453.
Story, J. A., 1981, The role of dietary fiber in lipid metabolism, Adv. Lipid Res. 18: 229–246.
Story, J. A., Baldino, A., Czarnecki, S. K., and Kritchevsky, D., 1981, Modification of liver cholesterol accumulation by dietary fiber in rats, Nutr. Rep. Int. 24: 1213–1219.
Tsai, A. C., Elias, J., Kelley, J. J., Lin, R. S. C., and Robson, J. R. K., 1976, Influence of certain dietary fibers on serum and tissue cholesterol levels in rats, J. Nutr. 106: 118–123.
Wells, A. F., and Ershoff, B. H., 1961, Beneficial effects of pectin in prevention of hypercholesterolemia and increase in liver cholesterol in cholesterol-fed rats, J. Nutr. 74: 87–92.
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Kritchevsky, D. (1986). Dietary Fiber and Atherosclerosis. In: Vahouny, G.V., Kritchevsky, D. (eds) Dietary Fiber. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2111-8_17
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DOI: https://doi.org/10.1007/978-1-4613-2111-8_17
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