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Human Growth pp 67–82Cite as

Control of Embryonic Growth Rate and Fetal Size in Mammals

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Abstract

All around us in our everyday life is evidence that the size and growth rates of mammals are under genetic control. We are all familiar with very small and very large dogs and do not expect to see either an adult Great Dane peering from a befurred lady’s bag or a Chihuahua dragging its owner for a walk. Such comments as “He’s big for his age” bear witness to our knowledge that growth toward adult stature follows a predictable time course. Adult size in mammals is thus said to be determinate and in general is achieved some time, perhaps many years, before death. This chapter is concerned for the most part with the genetic determinants involved in growth in a nonpathological setting. The focus is on the earliest stages of development at which differences in growth rate can be assessed and investigates what sorts of controls or constraints may be operative at that time. First of all, then, when do genetic differences in growth rate appear?

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Authors and Affiliations

  1. MRC Mammalian Development Unit, University College, London, NW1 2HE, England

    Michael H. L. Snow

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  1. Michael H. L. Snow
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  1. School of Public Health, University of California at Berkeley, Berkeley, California, USA

    Frank Falkner

  2. School of Medicine, University of California at San Francisco, San Francisco, California, USA

    Frank Falkner

  3. Institute of Child Health, University of London, London, England

    J. M. Tanner

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© 1986 Plenum Press, New York

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Snow, M.H.L. (1986). Control of Embryonic Growth Rate and Fetal Size in Mammals. In: Falkner, F., Tanner, J.M. (eds) Human Growth. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2101-9_4

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  • DOI: https://doi.org/10.1007/978-1-4613-2101-9_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9244-9

  • Online ISBN: 978-1-4613-2101-9

  • eBook Packages: Springer Book Archive

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