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Ion Movements in Skeletal Muscle in Relation to the Activation of Contraction

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Book cover Physiology of Membrane Disorders

Abstract

The dramatic event by which skeletal muscle, when stimulated, converts chemical energy into mechanical work has fascinated and puzzled physiologists for a long time(1) The interest with which the process of muscular activation has been studied was probably also aroused by the possibility of measuring accurately both the electrical activity associated with the outer membranous system and the mechanical output. The whole sequence of events which bridges these two processes has been intuitively called excitation-contraction coupling(2) Most of the current knowledge concerning this coupling is based on experiments performed in recent years, particularly on single amphibian and crustacean muscle fibers, a point to be borne in mind in any discussion on this subject.

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  1. Department of Cell Physiology, Ruhr University, Bochum, West Germany

    Hans Christoph Lüttgau

  2. Department of Zoology, La Trobe University, Melbourne, Australia

    George Dimitrie Stephenson

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    Thomas E. Andreoli M.D.  & Stanley G. Schultz M.D.  & 

  2. Yale University School of Medicine, New Haven, Connecticut, USA

    Joseph F. Hoffman Ph.D.

  3. University of California, San Diego La Jolla, California, USA

    Darrell D. Fanestil M.D.

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Lüttgau, H.C., Stephenson, G.D. (1986). Ion Movements in Skeletal Muscle in Relation to the Activation of Contraction. In: Andreoli, T.E., Hoffman, J.F., Fanestil, D.D., Schultz, S.G. (eds) Physiology of Membrane Disorders. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2097-5_28

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