The Interaction of Hormones with Biological Membranes

  • Darrell D. Fanestil


Hormones may be divided into two groups, based upon the cellular location from which they initiate their biological effects. The first group, composed of steroid hormones and thyroid hormone, generally exert their effects via initial interactions with a component (receptor) inside target cells. The second group, exemplified by peptide hormones and neurotransmitters, exert their effects via initial interactions with components (receptors) on the plasma membrane of target cells. In addition, the interaction of peptide hormones and neurotransmitters with membranes bears striking resemblance to the interaction with the plasma membrane of a number of other biological agents: prostaglandins, growth factors, and many pharmacological agents.


Hormone Receptor Insulin Receptor Adenylate Cyclase Phosphatidic Acid Peptide Hormone 
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Copyright information

© Plenum Publishing Corporation 1986

Authors and Affiliations

  • Darrell D. Fanestil
    • 1
  1. 1.Division of NephrologyUniversity of CaliforniaSan Diego, La JollaUSA

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