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Part of the book series: Developments in Veterinary Virology ((DVVI,volume 6))

Abstract

Several outbreaks of a varicella-like exanthematous disease have occurred in captive nonhuman primate populations. In each of these epizootics, the causative agent isolated from infected monkeys was determined to be a simian herpesvirus with properties resembling human varicella-zoster virus [VZV].

Furthermore, many of the clinical and pathological signs of simian varicella virus [SVV] infection in monkeys, including the vesicular skin rash and visceral lesions, are also characteristic of human varicella infection. It has also been found that the genome of SVV shares considerable homology with the genome of VZV. Therefore, in addition to causing sporadic epizootics in primate colonies, SVV infection of nonhuman primates also serves as a valuable laboratory model for human varicella infection, and is an important tool for virologists interested in investigating the pathogenesis, immunology and antiviral therapy of varicella-zoster.

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© 1988 Martinus Nijhoff Publishers, Boston

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Oakes, J.E., d’Offay, J.M. (1988). Simian Varicella Virus. In: Darai, G. (eds) Virus Diseases in Laboratory and Captive Animals. Developments in Veterinary Virology, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2091-3_9

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  • DOI: https://doi.org/10.1007/978-1-4613-2091-3_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9239-5

  • Online ISBN: 978-1-4613-2091-3

  • eBook Packages: Springer Book Archive

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