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Part of the book series: Developments in Veterinary Virology ((DVVI,volume 6))

Abstract

Yaba virus causes a disease in nonhuman primates which is characterized by formation of tumors that regress slowly; the animals are then susceptible to reinfection. The virus is an unclassified member of the poxvirus family. The molecular weight of the viral DNA is 119 × 106 dal tons. Assay is by foci or plaque formation. The virus grows slowly in tissue culture--the minimum replicative cycle is from 35 to 60 hours depending upon the cell line and the growth temperature. The virus replicates in the host cytoplasm, but viral DNA is present in the host cell nucleus late in the infection cycle. Virus infection does not inhibit host protein synthesis. Yaba virus initiates transformation of monkey kidney cells. Lipid granules accumulate in infected cells and in transformed cells.

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© 1988 Martinus Nijhoff Publishers, Boston

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Rouhandeh, H. (1988). Yaba Virus. In: Darai, G. (eds) Virus Diseases in Laboratory and Captive Animals. Developments in Veterinary Virology, vol 6. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2091-3_1

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  • DOI: https://doi.org/10.1007/978-1-4613-2091-3_1

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9239-5

  • Online ISBN: 978-1-4613-2091-3

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