Abstract
Alloimmunization to platelets frequently occurs in multitransfused patients and represents a major problem in platelet supportive therapy [1,2]. The provision of compatible platelets for alloimmunized patients remain difficult for the blood bank. Compatible platelet donors are usually selected based on HLA-compatibility between donor and recipient. Drawbacks of this approach are: a) a large HLA-typed donor panel is required that needs continuously updating and is therefore very expensive; 2) a significant percentage (13–31%) of HLA-matched platelet transfusions does not result in satisfactory posttransfusion platelet increments [3–61].
Supported by a grant from the Josephine Nefkens Foundation.
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© 1987 Martinus Nijhoff Publishing, Boston
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Sintnicolaas, K., Sizoo, W., Bolhuis, R.L.H. (1987). Prospective Selection of Compatible Platelet Donors for Alloimmunized Patients by an ELISA Platelet Cross-Match Only. In: Sibinga, C.T.S., Das, P.C., Engelfriet, C.P. (eds) White cells and platelets in blood transfusion. Developments in Hematology and Immunology, vol 19. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2089-0_6
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DOI: https://doi.org/10.1007/978-1-4613-2089-0_6
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