Skip to main content
SpringerLink
Log in

Regulation of Gene Expression from the Polyoma Late Promoter

  • Chapter
Molecular Aspects of Papovaviruses

Part of the book series: Developments in Molecular Virology ((DMVI,volume 9))

  • 26 Accesses

Abstract

An experimental system has been developed in which foreign coding sequences for easily assayed genes or selectable markers are placed under the control of the polyoma late promoter. The use of this system has allowed the elucidation of the cisacting elements that control expression from this promoter and the demonstration of transactivation of this promoter by the viral early proteins. In addition to these forms of transcriptional control, the results also suggest that late transcription, both in polyoma transformed cells and early in the course of a lytic infection, may also be regulated at a posttranscriptional level.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Tooze, J. DNA tumor virus: Molecular Biology of Tumor Viruses, part 2. Cold Spring Harbor Laboratory, Cold Spring Harbor N.Y., 1980.

    Google Scholar 

  2. Franke, B. and Eckhart, W. Virology 55:1 27–135, 1973.

    Google Scholar 

  3. Gaudray, P., Tyndall, C., Kamen, R. and Cuzin, F. Nucleic Acids Res. 9:5697–5710, 1981.

    Article  PubMed  CAS  Google Scholar 

  4. Dilworth, S.M., Cowie, A., Kamen, R. and Griffin, B.E. Proc. Natl. Acad. Sci. U.S.A. 81:1941–1945, 1984.

    Article  PubMed  CAS  Google Scholar 

  5. Pomerantz, B.J., Mueller, C.R. and Hassell, J.A. J. Virol. 47:600–610, 1983.

    PubMed  CAS  Google Scholar 

  6. Fenton, R.G. and Basilico, C. Virology 121:384–392, 1982.

    Article  PubMed  CAS  Google Scholar 

  7. Farmerie, W.G. and Folk, W.R. Proc. Natl. Acad. Sci. U.S.A. 81:6919–6923, 1984.

    Article  PubMed  CAS  Google Scholar 

  8. Icheson, N.H. Proc. Natl J Acad. Sci. U.S.A. 75:4754–4758, 1978.

    Article  Google Scholar 

  9. Treisman, R. Nucleic Acids Res. 8:4867–4888, 1980.

    Article  PubMed  CAS  Google Scholar 

  10. Soeda, E., Arrand, A., Smolar, N., Walsh, J. and Griffin, B., 1980. Nature 283:445–453.

    Article  PubMed  CAS  Google Scholar 

  11. Legon, S. J. Mol. Biol. 134:219–240, 1979.

    Article  CAS  Google Scholar 

  12. Adami, G.R. and Carmichael, G.G. J. Virol. 58:417–425, 1986.

    PubMed  CAS  Google Scholar 

  13. Luthman, H., Nilsson, M.G. and Magnusson, G. J. Mol. Biol. 161:533–550, 1982.

    Article  CAS  Google Scholar 

  14. Katinka, M. and Yaniv, M. J. Virol. 47:244–248, 1983.

    PubMed  CAS  Google Scholar 

  15. Cowie, A. and Kamen, R. J. Virol. 52:750–760, 1984.

    PubMed  CAS  Google Scholar 

  16. de Villiers, J. and Schaffner, W. Nucleic Acids Res. 9:6251–6264, 1981.

    Article  PubMed  Google Scholar 

  17. Tyndall, C., La Mantia, G., Thacker, C.M., Favaloro, J. and Kamen, R. Nucleic Acids Res. 9:6231–6250, 1981.

    Article  PubMed  CAS  Google Scholar 

  18. Banerji, J., Rusconi, S. and Schaffner, W. Cell 27:299–308, 1981.

    Article  PubMed  CAS  Google Scholar 

  19. Jat, P., Novak, U., Cowie, A., Tyndall, C. and Kamen, R. Mol. Cell. Biol. 2:737–751, 1982.

    PubMed  CAS  Google Scholar 

  20. Cowie, A., Tyndall, C. and Kamen, R. Nucleic Acids Res. 9:6305–6322, 1981.

    Article  PubMed  CAS  Google Scholar 

  21. de Villiers, J., Schaffner, W., Tyndall, C., Lupton, S. and Kamen, R. Nature 312:242–246, 1984.

    Article  PubMed  Google Scholar 

  22. Basilico, C. Pharmac. Ther. 26:235–272, 1985.

    Article  Google Scholar 

  23. Treisman, R., Novak, V., Favaloro, J. and Kamen, R. Nature 292:595–600, 1981.

    Article  PubMed  CAS  Google Scholar 

  24. Pillegrini, S., Dailey, L. and Basilico, C. Cell 3:943–949, 1984.

    Article  Google Scholar 

  25. Kern, F.G. and Basilico, C. Mol. Cell. Biol. 5:797–807, 1985.

    PubMed  CAS  Google Scholar 

  26. Kern, F.G., Dailey, L. and Basilico, C. Mol. Cell. Biol. 5:2070–2079, 1985.

    PubMed  CAS  Google Scholar 

  27. Kern, F.G., Pellegrini, S. and Basilico, C. In: Cancer Cells, vol. 4, DNA Tumor Viruses: Control of Gene Expression and Replication. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y., in press.

    Google Scholar 

  28. Kern, F.G., Pellegrini, S., Cowie, A. and Basilico, C. J. Virol., in press.

    Google Scholar 

  29. Colantuoni, V., Dailey, L. and Basilico, C. Proc. Natl. Acad. Sci. U.S.A. 77:3850–3854.

    Google Scholar 

  30. Frischauf, A.M., Lehrach, H., Poutska, A. and Murray, N. J. Mol. Biol. 170:824–842.

    Google Scholar 

  31. Basilico, C., Fenton, R.G. and Delia Valle, G. In: Expression of Differentiated Functions in Cancer Cells (Ed. R.F. Revoltella), Raven Press, New York, 1982, pp. 323–335.

    Google Scholar 

  32. Colberre-Garapin, F., Horodniceanu, F., Kourilsky, P. and Garapin, A.C. J. Mol. Biol. 150:1–14, 1981.

    Article  Google Scholar 

  33. Zenke, M., Grundstrom, T., Matthes, H., Winzerith, M., Schatz, C., Wildeman, A. and Chambon, P. EMBO J. 5:387–397, 1986.

    PubMed  CAS  Google Scholar 

  34. Herbomel, P., Bourachot, B. and Yaniv, M. Cell 39:653–662, 1984.

    Article  PubMed  CAS  Google Scholar 

  35. Maione, R., Passananti, C., De Simone, V., Delli-Bovi, P., Augusti-Tocco, G. and Amati, P. EMBO J. 4:3215–3221, 1985.

    PubMed  CAS  Google Scholar 

  36. Weiher, H., Konig, M. and Gruss, P. Science 219:626–631, 1983.

    Article  PubMed  CAS  Google Scholar 

  37. Veldman, G.M., Lupton, S. and Kamen, R. Mol. Cell. Biol. 5:649–658, 1985.

    PubMed  CAS  Google Scholar 

  38. Hearing, P. and Shenk, T. Cell 33:695–703, 1983.

    Article  PubMed  CAS  Google Scholar 

  39. Gorman, CM., Moffat, L.F. and Howard, B.H. Mol. Cell. Biol. 2:1044–1051, 1982.

    PubMed  CAS  Google Scholar 

  40. Wong, G.G., Witch, J.S., Temple, P.A., Wilkins, K.M., Leary, A.C., Luxenberg, D.P., Jones, S.S., Brown E.L., Kay, R.M., Orr, E.C., Shoemaker, C, Golde, D.W., Kaufman, R.J., Hewick, R.M., Wang, E.A. and Clark, S.C. Science 228:810–815, 1985.

    Article  PubMed  CAS  Google Scholar 

  41. Lanoix, J., Tseng, R.W. and Acheson, N.H. J. Virol. 58:733–742, 1986.

    PubMed  CAS  Google Scholar 

  42. Izant, J.G. and Weintraub, H. Cell 36:1007–1015, 1984.

    Article  PubMed  CAS  Google Scholar 

  43. Kamen, R., Jat, P., Treisman, R. and Favaloro, J. J. Mol. Biol. 159:189–224, 1982.

    Article  CAS  Google Scholar 

  44. Fenton, R.G. and Basilico, C. Proc. Natl. Acad. Sci. U.S.A. 79:7142–7146, 1982.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pathology, New York University School of Medicine, New York, New York, 10016, USA

    F. G. Kern, P. Delli-Bovi, S. Pellegrini & C. Basilico

Authors
  1. F. G. Kern
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. Delli-Bovi
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. S. Pellegrini
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. C. Basilico
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. The Weizmann Institute of Science, Rehovot, Israel

    Yosef Aloni

Rights and permissions

Reprints and permissions

Copyright information

© 1987 Martinus Nijhoff Publishers

About this chapter

Cite this chapter

Kern, F.G., Delli-Bovi, P., Pellegrini, S., Basilico, C. (1987). Regulation of Gene Expression from the Polyoma Late Promoter. In: Aloni, Y. (eds) Molecular Aspects of Papovaviruses. Developments in Molecular Virology, vol 9. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2087-6_7

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-2087-6_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9237-1

  • Online ISBN: 978-1-4613-2087-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation