Abstract
This report concerns nine cases of diabetes mellitus associated with infectious hepatitis, an epidemic of which swept through eastern Nigeria between 1970 and 1972 following the Nigerian civil war. All the patients suffered from classical acute infectious hepatitis and, as they appeared to be recovering from this infection, developed symptoms and signs of diabetes mellitus. They responded quickly to treatment and after a few months, the diabetes clinically disappeared. Corticosteroid-glucose tolerance tests carried out in four of these patients, 12 to 30 months after the clinical remission of their diabetes, were normal. Contact with the remaining five patients was lost after a few months follow-up following clinical remission, probably because they remained well. It is postulated that the virus that caused the acute infectious hepatitis may have damaged pancreatic islet cells, partially or temporarily, to produce an acute remittant form of diabetes mellitus in these patients.
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© 1987 Martinus Nijhoff Publishing, Boston
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Adi, F.C. (1987). Diabetes Mellitus Associated with Epidemic Infectious Hepatitis in Nigeria. In: Becker, Y. (eds) Virus Infections and Diabetes Mellitus. Developments in Medical Virology, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2085-2_11
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DOI: https://doi.org/10.1007/978-1-4613-2085-2_11
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9236-4
Online ISBN: 978-1-4613-2085-2
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