Abstract
In 1971, we were worried about our results of open heart surgery. Although we had a reasonable overall 30-day mortality of around 10%, we had an additional rate of cerebral complications of around 20%. These complications were often of a passing nature, but all too frequently the final mental or neurological state of the patient marred an otherwise impeccable surgical result. Furthermore, the neurological death rate in our material was high, with 4% of the adults operated on dying with or from neurological complications; these cases constituted 40% of all patients dying. Matters were clearly not satisfactory.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Kornfeld DS, Zimberg S, Malm, JR: (1965) Psychiatric complicatins of open-heart surgery. New Engl J Med 273:287.
Aberg T: (1974) Effect of open heart surgery on intellectual function. Scand J Thorac Cardiovasc Surg, Suppl 15.
Aberg T, Kihlgren M: (1977) Cerebral protection during open-heart surgery. Thorax 32:525.
Aberg T, Kihlgren M: (1977) Cerebral protection during open heart surgery. Thoraxchirurgie 25:146.
Aberg T, Kihlgren M, Jonsson L, Stjernlöf K, Lönn U, Rystedt T, Tydén H, Westerholm C-J, Taube A: (1982) Improved cerebral protection during open-heart surgery. A psychometric investigation on 339 patients. In Psychopathological and Neurological Dysfunctions Following Open-Heart Surgery, Becker et al. (eds.). Heidelberg: Springer-Verlag Berlin.
Aberg T, Ahlund P, Kihlgren M: (1983) Intellectual function late after open-heart operation. Ann Thorac Surg 36:680.
Aim PO, Frithz G, Ronquist G: (1979) Adenylate kinase activity in cerebrospinal fluid of schizophrenic and certain other psychiatric symptomatologies. Acta Psychiatr Scand 59:517–524.
Frithz G, Ronquist G, Andersson B: (1980) Drug action on adenylate kinase activity in cerebrospinal fluid of arteriosclerotic patients. Experientia 36:1409–1410.
Jonsson I, Briem H, Ronquist G: (1979) Cerebrospinal fluid content of adenylate kinase, lactate and glutathione in patients with meningitis. Scand J Infect Dis 11:11–15.
Terent A, Ronquist G, Bergström K, Hällgren R, Åberg H. (1980) Ischemic edema in stroke. A parallel study with computed tomography and cerebrospinal fluid markers of disturbed brain cell metabolism. Stroke 12:33–40.
Ronquist G, Frithz G: (1979) Adenylate kinase activity and glutathione concentration of cerebrospinal fluid in different neurological disorders. Eur Neurol 18:106–110.
Aberg T, Ronquist G, Tydén H, Ahlund P, Bergström K: (1982) Release of adenylate kinase into cerebrospinal fluid during open-heart surgery and its relation to postoperative intellectual function. Lancet 1, 1139–1142.
Aberg T, Ronquist G, Tydén H, Brunnkvist S, Hultman J, Bergström K, Lilja A: (1984) Adverse effects on the brain in cardiac operations as assessed by biochemical, psychometric, and radiologic methods. J Thorac Cardiovasc Surg 87:99–105.
Hill JD, Aguilar MJ, Baranco A, Lanerolle P, Gerbode F: (1969) Neuropathological manifestations of cardiac surgery. Ann Thorac Surg 7:409.
Osborn JJ, Swank RL, Hill JD, Aguilar MJ, Gerbode F: (1970) Clinical use of a dacron wool filter during perfusion for open-heart surgery. J Thorac Cardiovasc Surg 60:575.
Rådegran, K: (1972) Circulatory and respiratory effects of induced platelet aggregation. An experimental study in dogs. Acta Chir Scand, Suppl 420.
Aberg et al: (In press).
Aberg et al: (In press) Scand J Thorac Cardiovasc Surg.
Shaw PJ, Bates D, Cartildge NEF, Heaviside D, Julian DG, Shaw DA: (1985) Early neurological complications of coronary artery bypass surgery. Br Med J 291:1384–1387.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1988 Martinus Nijhoff Publishing, Boston
About this chapter
Cite this chapter
Åberg, T. (1988). Cerebral Injury During Open Heart Surgery: Studies Using Functional, Biochemical, and Morphological Methods. In: Hilberman, M. (eds) Brain Injury and Protection During Heart Surgery. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2075-3_1
Download citation
DOI: https://doi.org/10.1007/978-1-4613-2075-3_1
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9231-9
Online ISBN: 978-1-4613-2075-3
eBook Packages: Springer Book Archive