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Steroid and Sterol Hormone Action pp 1–23Cite as

Immunocharacterization of the Nuclear Acceptor Sites for the Avian Oviduct Progesterone Receptor

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Abstract

It is well known that steroid hormones, certain vitamins and sterols, enter target cells and bind to specific protein receptors in the cytoplasm or nucleus (1–4). This binding is saturable, high affinity, and steroid specific. Once bound by the steroid, the receptor undergoes chemical/conformation change, termed “activation,” which enables the receptor (as a complex with the steroid) to bind to nuclear acceptor sites on the nuclear chromatin (5,6) or nuclear matrix (7,8). It is generally accepted that the binding of the steroid receptor complex to these nuclear acceptor sites is a prerequisite for the steroid regulation of gene transcription and possibly post-transcriptional events.

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References

  1. Thrall, C, Webster, R.A. and Spelsberg, T.C. In: The Cell Nucleus, Vol. VI, Part 1, (Ed. H. Busch), Academic Press, New York, 1978, pp. 461–529.

    Google Scholar 

  2. Spelsberg, T.C, Littlefield, B.A., Seelke, R., Martin-Dani, G., Toyoda, H., Boyd-Leinen, P., Thrall, C. and Kon, O.L. Recent Prog. Hormone Res. 39:463–517, 1983.

    CAS  Google Scholar 

  3. Moore, J.T., Norvitch, M.D., Wieben, E.D. and Veneziale, C.M. J. Biol. Chem. 259:14750–14756, 1984.

    PubMed  CAS  Google Scholar 

  4. Jensen, E.V. and DeSombre, E.R. Ann. Rev. Biochem. 41:203–230, 1972.

    Article  PubMed  CAS  Google Scholar 

  5. Spelsberg, T.C., Knowler, J., Boyd, P.A., Thrall, C.L. and Martin-Dani, G. J. Steroid Biochem. 11:373–388, 1979.

    Article  PubMed  CAS  Google Scholar 

  6. Spelsberg, T.C. In: Biochemical Actions of Hormones, (Ed. G. Litwack), Academic Press, Vol. 9, 1982, pp. 141–204.

    Google Scholar 

  7. Barrack, E.R. and Coffey, D.S. J. Biol. Chem. 255:7265–7275, 1980.

    PubMed  CAS  Google Scholar 

  8. Barrack, E.R. and Coffey, D.S. Recent Prog. Hormone Res. 38:133–195, 1982.

    CAS  Google Scholar 

  9. Martin-Dani, G. and Spelsberg, T.C. Biochemistry 24:6988–6997, 1985.

    Article  Google Scholar 

  10. Ruh, T.S. and Spelsberg, T.C. Biochem. J. 210:905–912, 1982.

    Google Scholar 

  11. Ruh, T.S., Ross, Jr., P., Wood, D.M. and Keene, J.L. Biochem. J. 200:133–142, 1981.

    PubMed  CAS  Google Scholar 

  12. Ross, Jr. P. and Ruh, T.S. Biochim. Biophys. Acta 782:18–25, 1984.

    PubMed  CAS  Google Scholar 

  13. Ruh, M.F., Singh, R.K., Bellone, C.J. and Ruh, T.S. Biochim. Biophys. Acta 844:24–33, 1985.

    Article  PubMed  CAS  Google Scholar 

  14. Lopez, A., Burgos, J. and Ventanas, J. Internal J. Biochem. 17:1207–1211, 1985.

    Article  CAS  Google Scholar 

  15. Spelsberg, T.C, Gosse, B., Littlefield, B., Toyoda, H. and Seelke, R. Biochemistry 23:5103–5112, 1984.

    Article  PubMed  CAS  Google Scholar 

  16. Cobb, A. and Leavitt, W.W. (abstract). 67th Annual Meeting of the Endocrine Society, June 19–21 (Baltimore, MD), pp. 83, No. 330.

    Google Scholar 

  17. Perry, B.N. and Lopez, A. Biochem. J. 176:873–883, 1978.

    PubMed  CAS  Google Scholar 

  18. Klyzsejko-Stefanowicz, L., Chui, J.F., Tsai, Y.H. and Hnilica, L.S. Natl. Acad. Sci. USA 73:1954–1958, 1976.

    Article  CAS  Google Scholar 

  19. Hamana, K. and Iwai, K. J. Biochem. (Tokyo) 83:279–286, 1978.

    CAS  Google Scholar 

  20. Payvar, F., Wrange, O., Carlstedt-Duke, J., Okret, S., Gustafsson, J.A. and Yamamato, K. Proc. Natl. Acad. Sci. USA 78:6628–6632, 1981.

    Article  PubMed  CAS  Google Scholar 

  21. Chandler, V.L., Maler, B.A. and Yamamoto, K.R. Cell 33:489–499, 1983.

    Article  PubMed  CAS  Google Scholar 

  22. Payvar, F., DeFranco, D., Firestone, G.L., Edgar, B., Wrange, O., Okret, S., Gustafsson, J.A. and Yamamoto, K.R. Cell 35:381–392.

    Google Scholar 

  23. Lee, F., Mulligan, R., Berg P. and Ringold, G. Nature 294:228–232, 1981.

    Article  PubMed  CAS  Google Scholar 

  24. Compton, J.G., Schrader, W.T. and O’Malley, B.W. Biochem. Biophys. Res. Commun. 105:96–104, 1982.

    Article  PubMed  CAS  Google Scholar 

  25. Dean, D.C, Knoll, B.J., Riser, M.E. and O’Malley, B.W. Nature 305:551–554, 1983.

    Article  PubMed  CAS  Google Scholar 

  26. Bailley, A., Atger, M., Atger, P., Cerbon, M.A., Alizon, M., Vu Hai, M.T., Logeat, F. and Milgrom, E. J. Biol. Chem. 258:10384–10389, 1983.

    Google Scholar 

  27. Mulvihill, E.R., LePennec, J.P. and Chambon, P. Cell 28:621–632, 1982.

    Article  PubMed  CAS  Google Scholar 

  28. Miller, P.A., Ostrowski, M.C, Hager, G.L. and Simons, Jr., S.S. Biochemistry 23:6883–6889, 1984.

    Article  PubMed  CAS  Google Scholar 

  29. deAhe, D., Janich, S., Scheidert, C, Renkawitz, R., Schutz, G. and Beato, M. Nature 313:706–709, 1985.

    Article  Google Scholar 

  30. Jost, J-P., Seldram, M., Geiser, M. Proc. Natl. Acad. Sci. USA 81:429–433, 1984.

    Article  PubMed  CAS  Google Scholar 

  31. Goldberger, A., Littlefield, B.A., Katzmann, J. and Spelsberg, T.C Endocrinology 118:2235–2261, 1985.

    Article  Google Scholar 

  32. Spelsberg, T.C. Biochemistry 22:13–21, 1983.

    Article  PubMed  CAS  Google Scholar 

  33. Boyd, P.A. and Spelsberg, T.C. Biochemistry 18:3685–3690, 1979.

    Article  PubMed  CAS  Google Scholar 

  34. Boyd-Leinen, P., Gosse, B., Martin-Dani, G. and Spelsberg, T.C. J. Biol. Chem. 259:2411–2421, 1984.

    PubMed  CAS  Google Scholar 

  35. Puri, R.K,, Grandies, P., Dougherty, J.J. and Toft, D.O. J. Biol. Chem. 257:10831–10837, 1982.

    PubMed  CAS  Google Scholar 

  36. Dougherty, J.J., Puri, R.K. and Toft, D.O. J. Biol. Chem. 259:8004–8009, 1984.

    PubMed  CAS  Google Scholar 

  37. Hora, J., Gosse, B., Rasmussen, K. and Spelsberg, T.C. Endocrinology 119:1118–1125, 1986.

    Article  PubMed  CAS  Google Scholar 

  38. Boyd-Leinen, P.A., Fournier, D. and Spelsberg, T.C. Endocrinology 111:30–36, 1982.

    Article  PubMed  CAS  Google Scholar 

  39. Thrall, T.C. and Spelsberg, T.C. Biochemistry 19:4130–4138, 1980.

    Article  PubMed  CAS  Google Scholar 

  40. Littlefield, B.A. and Spelsberg, T.C. Endocrinology 117:412–424, 1984.

    Article  Google Scholar 

  41. Hora, J., Horton, M.J., Toft, D.O. and Spelsberg, T.C. Proc. Natl. Acad. Sci. USA, In press, 1986.

    Google Scholar 

  42. Toyoda, H., Seelke, R., Littlefield, B.A. and Spelsberg, T.C. Proc. Natl. Acad. Sci. USA 82:4722–4726, 1985.

    Article  PubMed  CAS  Google Scholar 

  43. Spelsberg, T.C, Pikier, G.M. and Webster, R.A. Science 194:197–199, 1976.

    Article  PubMed  CAS  Google Scholar 

  44. Kon, O.L. and Spelsberg, T.C. Endocrinology 111:1925–1936, 1982.

    Article  PubMed  CAS  Google Scholar 

  45. Singh, R.K., Ruh, M.F. and Ruh, T.S. Biochem. Biophys. Acta 800:33–40, 1984.

    PubMed  CAS  Google Scholar 

  46. Chuknyiska, R.S., Haji, M., Foote, R.H. and Roth, G.S. Endocrinology 115:836–838, 1984.

    Article  PubMed  CAS  Google Scholar 

  47. Spelsberg, T.C., Reinhart, G.D. and Barham, S. Analytical Biochem. 143:237–248, 1984.

    Article  CAS  Google Scholar 

  48. Pikier, G.M., Webster, R.A. and Spelsberg, T.C. Biochem. J. 156:399–408, 1976.

    Google Scholar 

  49. Greene, G.L., Closs, L.E., Fleming, H., DeSombre, E.R. and Jensen, E.V. Proc. Natl. Acad. Sci. USA 74:3681–3685, 1977.

    Article  PubMed  CAS  Google Scholar 

  50. Webster, R., Pikier, G. and Spelsberg, T. Biochem. J. 156:409–419, 1976.

    PubMed  CAS  Google Scholar 

  51. Spelsberg, T., Webster, R. and Pikier, G. Nature. 262:65–67, 1976.

    Article  PubMed  CAS  Google Scholar 

  52. Spelsberg, T.C. Biochem. J. 156:391–398, 1976.

    PubMed  CAS  Google Scholar 

  53. Hewish, D.R. and Burgoyne, L.A. Biochem. Biophys. Res. Comm. 52:475–481, 1973

    Article  PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Biochemistry and Molecular Biology, Mayo Clinic and Mayo Graduate School of Medicine, Rochester, MN, 55905, USA

    A. Goldberger, M. Horton & T. C. Spelsberg

Authors
  1. A. Goldberger
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  2. M. Horton
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  3. T. C. Spelsberg
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Editor information

Editors and Affiliations

  1. Department of Biochemistry and Molecular Biology, Mayo Clinic and Mayo Graduate School of Medicine, Rochester, MN, 55905, USA

    T. C. Spelsberg

  2. Department of Medicine, Endocrine Research Unit, Mayo Clinic and Foundation, Rochester, 55905, MN, USA

    R. Kumar

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© 1987 Martinus Nijhoff Publishing, Boston

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Goldberger, A., Horton, M., Spelsberg, T.C. (1987). Immunocharacterization of the Nuclear Acceptor Sites for the Avian Oviduct Progesterone Receptor. In: Spelsberg, T.C., Kumar, R. (eds) Steroid and Sterol Hormone Action. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2073-9_1

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  • DOI: https://doi.org/10.1007/978-1-4613-2073-9_1

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9230-2

  • Online ISBN: 978-1-4613-2073-9

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