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Ultrastructural aspects of the turnover of stomach mucosal epithelium

  • Chapter
Ultrastructure of the Digestive Tract

Part of the book series: Electron Microscopy in Biology and Medicine ((EMBM,volume 4))

Abstract

The epithelia of the gastric body and fundus are comprised of gastric pits (foveolae) and fundic glands. The transitional portion between the pit and the gland, corresponding to the isthmus and neck region, is the generative cell zone (1,2), where mitosis takes place. Most cells generated there migrate upwards along the gastric pit to the surface of the stomach to become surface mucous cells and are finally disposed of into the gastric lumen; whereas a few cells in the generative zone move downwards to differentiate into mucous neck cells, parietal cells, and chief cells, and eventually cell death occurs at the base of the gland, though their turnover is much slower than that of surface mucous cells.

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Author information

Authors and Affiliations

  1. Department of Anatomy, Osaka University Medical School, 4-3-57 Nakanoshima, 530, Kita-Ku, Osaka, Japan

    Haruyuki Tatsumi & Hisao Fujita

Authors
  1. Haruyuki Tatsumi
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  2. Hisao Fujita
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Editor information

Editors and Affiliations

  1. Department of Anatomy, Faculty of Medicine University of Rome, Rome, Italy

    P. M. Motta M.D., Ph.D.

  2. Department of Anatomy, Osaka University Medical School, Osaka, Japan

    H. Fujita M.D.

  3. Department of Anatomy, University Medical School, Rome, Italy

    S. Correr Ph.D.

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© 1988 Martinus Nijhoff Publishing, Boston

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Tatsumi, H., Fujita, H. (1988). Ultrastructural aspects of the turnover of stomach mucosal epithelium. In: Motta, P.M., Fujita, H., Correr, S. (eds) Ultrastructure of the Digestive Tract. Electron Microscopy in Biology and Medicine, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2071-5_4

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  • DOI: https://doi.org/10.1007/978-1-4613-2071-5_4

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9229-6

  • Online ISBN: 978-1-4613-2071-5

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