Abstract
The saluretic agent muzolimine (MZ) induces “in vivo” changes in urinary pattern similar to those observed with loop diuretics, as furosemide (FUR), bumetanide (BUM) or ethacrinic acid (ETHA) (1). These drugs inhibit NaK2Cl cotransport (COT) in both the luminal side: of the thick ascending limb of Henle’s loop (TAL) and in erythrocytes (RBC) (2). Thus, RBC may be an useful model to study the cellular effects of MZ (2). In this paper we studied RBC cation transport pathways in the presence of MZ.
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© 1987 Martinus Nijhoff Publishing, Boston
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Montanari, A., Guerra, A., Sani, E., Novarini, A. (1987). Effects of Muzolimine on Cation Transport in Human Erythrocytes. In: Andreucci, V.E., Dal Canton, A. (eds) Diuretics: Basic, Pharmacological, and Clinical Aspects. Developments in Nephrology, vol 18. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2067-8_9
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DOI: https://doi.org/10.1007/978-1-4613-2067-8_9
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9227-2
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