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Inhibition of the Erythrocyte Na+, K+-Pump by Mammalian Lignans: A Possible Link with Endogenous Digitalis

  • P. Braquet
  • N. Senn
  • A. Esanu
  • R. Garay
Chapter
Part of the Developments in Nephrology book series (DINE, volume 18)

Abstract

Natural products formed by oxidative dimerization of phenols, most lignans belong to the vegetal world. However, related structures have been found recently in human and animal urines (1,2). These mammalian lignans are characterized by the presence of the meta hydroxyl group on each aryl cycle of a dibenzyl-gamma-butyrolactone framework (Fig. 1, ref 3).

Keywords

Pump Activity Sodium Pump Apparent Affinity Oxidative Dimerization Animal Urine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Martinus Nijhoff Publishing, Boston 1987

Authors and Affiliations

  • P. Braquet
    • 1
  • N. Senn
    • 2
  • A. Esanu
    • 1
  • R. Garay
    • 2
  1. 1.Institut Henri BeaufourLe Plessis RobinsonFrance
  2. 2.INSERM U7, Hôpital NeckerParisFrance

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