Muzolimine as Treatment of Ascites from Hepatic Chirrosis
The antagonists of Aldosterone are considered the first choice diuretics in the treatment of ascites from liver cirrhosis. They are able to induce a slow and progressive weight loss without potassium depletion(l). Their long term use causes anyway hyperkalaemia and hyperchloraemic acidosis (2) and their efficacy is reduced in long lasting ascites. In such a case the more drastic loop diuretics are required. These have however serious side effects in cirrhotics more than in other patients (hypokalaemia, encephalopathy, hepatorenal syndrome) (3).
KeywordsCreatinine Aldosterone Muzolimine
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