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Plasma Cell Dyscrasias: Definition and Diagnostic Evaluation

  • Robert A KyleJr.
Part of the Topics in the Neurosciences book series (TNSC, volume 5)

Abstract

The plasma cell dyscrasias (table 1–1), which are synonymous with monoclonal gammopathies, are characterized by proliferation of a single clone of plasma cells which produces a homogeneous monoclonal (M) protein. Each monoclonal protein consists of two heavy polypeptide chains of the same class and subclass and two light polypeptide chains of the same type. In contrast, polyclonal immunoglobulins consist of one or more heavy-chain classes and both light-chain types.

Keywords

Multiple Myeloma Familial Mediterranean Fever Carpal Tunnel Syndrome Spinal Muscular Atrophy Amyloid Fibril 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Martinus Nijhoff Publishing, Boston 1987

Authors and Affiliations

  • Robert A KyleJr.
    • 1
  1. 1.Division of Hematology and Internal MedicineMayo Medical School, Mayo Clinic and Mayo FoundationsRochesterUSA

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