Abstract
The prolonged action of clinically available beta-adrenoreceptor blockers complicates their use in cases of unstable hemodynamic condition. In such cases, hemodynamic deterioration may acutely increase the dependence of the circulation on sympathetic tone. This is especially valid in elderly patients because they have a decreased sympathetic tone and less potent compensatory circulatory mechanisms than do younger patients. Moreover, some of the adverse effects of beta-adrenoreceptor blockers may be especially deleterious if they are of long duration.
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© 1988 Martinus Nijhoff Publishing, Boston
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Schneeweiss, A., Schettler, G. (1988). Esmolol. In: Cardiovascular Drug Therapy in the Elderly. Developments in Cardiovascular Medicine, vol 72. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2063-0_42
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DOI: https://doi.org/10.1007/978-1-4613-2063-0_42
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9225-8
Online ISBN: 978-1-4613-2063-0
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