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Amiodarone

  • Chapter
Cardiovascular Drug Therapy in the Elderly

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 72))

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Abstract

Amiodarone is a benzofuran derivative with class 3 antiarrhythmic properties and an antianginal effect. It was originally used as an antianginal agent and is still used for this indication, especially in France. Its main use today is for treatment of arrhythmias. Amiodarone is effective in termination and prevention of almost all types of supraventricular and ventricular arrhythmias. The antiarrhythmic effect of amiodarone is associated with prolongation of the QT interval. Amiodarone is also a potent coronary and systemic vasodilator. Amiodarone differs from all other antiarrhythmic agents in its structure. It also produces several specific adverse effects such as impairment of thyroid function, ocular microdeposits, skin lesions, and pulmonary toxicity.

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Author information

Authors and Affiliations

  1. Geriatric Cardiology Research Foundation, Tel-Aviv, Israel

    Adam Schneeweiss M.D.

  2. Department of Medicine, University of Heidelberg, Germany

    Gotthard Schettler M.D.

Authors
  1. Adam Schneeweiss M.D.
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  2. Gotthard Schettler M.D.
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© 1988 Martinus Nijhoff Publishing, Boston

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Schneeweiss, A., Schettler, G. (1988). Amiodarone. In: Cardiovascular Drug Therapy in the Elderly. Developments in Cardiovascular Medicine, vol 72. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2063-0_33

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  • DOI: https://doi.org/10.1007/978-1-4613-2063-0_33

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9225-8

  • Online ISBN: 978-1-4613-2063-0

  • eBook Packages: Springer Book Archive

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