Skip to main content

Clinical Trials in Hypertension and Congestive Heart Failure

  • Chapter
Pharmacological Aspects of Heart Disease

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 68))

  • 35 Accesses

Abstract

In cardiovascular disease, many treatments aim to prevent future disease complications and/or premature death. This applies both to asymptomatic conditions such as hypertension and to symptomatic illnesses such as congestive heart failure (CHF). The main purpose of this review is to consider the results of randomized clinical trials in these conditions, and to examine the overall effects of drug treatment on all-cause mortality. For the hypertension trials, stroke and coronary heart disease (CHD) incidence will also be reviewed.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Conn, J.N., Archibald, D.G., Ziesche, S., Franciosa, J.A., Harston, W.E., Tristani, F.E., Dunkman, W.B., Jacobs, W., Francis, G.S., Flohr, K.H., Goldman, S., Cobb, F.R., Shah, P.M., Saunders, R., Fletcher, R.D., Loeb, H.S., Hughes, V.C. and Baker, B. N. Engl. J. Med. 314: 1547–1552, 1986.

    Article  Google Scholar 

  2. Cutler, J.A. and Furberg, CD. Prev. Med. 14:499–519, 1985.

    Article  PubMed  CAS  Google Scholar 

  3. MacMahon, S.W., Cutler, J.A., Furberg, CD., and Payne, G.H. Progr. Cardiovasc. Dis. 1986 (in press).

    Google Scholar 

  4. Furberg, CD. and Yusuf, S. Am. J. Cardiol. 55:1110–1113, 1985.

    Article  PubMed  CAS  Google Scholar 

  5. Furberg, CD. and Yusuf, S. Adv. Cardiol. 34, 1986.

    Google Scholar 

  6. Yusuf, S., Peto, R., Lewis, J., Collins, R. and Sleight, P. Progr. Cardiovasc. Dis. 27:335–371, 1985.

    Article  CAS  Google Scholar 

  7. Medical Research Council Working Party. Br. Med. J. 291: 97–104, 1985.

    Article  Google Scholar 

  8. Hypertension Detection and Follow-up Program Cooperative Group. JAMA 242:2562–2571, 1979.

    Article  Google Scholar 

  9. Croog, S.H., Levine, S., Testa, M.A., Brown, B., Bulpitt, C.J., Jenkins, CD., Klerman, G.L. and Williams, G.H. N. Engl. J. Med. 314:1657–1664, 1986.

    Article  CAS  Google Scholar 

  10. Multiple Risk Factor Intervention Trial Research Group. Am. J. Cardiol. 55:1–15, 1985.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1987 Martinus Nijhoff Publishing, Boston

About this chapter

Cite this chapter

Furberg, C.D., Cutler, J.A., Macmahon, S.W., Yusuf, S. (1987). Clinical Trials in Hypertension and Congestive Heart Failure. In: Beamish, R.E., Panagia, V., Dhalla, N.S. (eds) Pharmacological Aspects of Heart Disease. Developments in Cardiovascular Medicine, vol 68. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2057-9_7

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-2057-9_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9222-7

  • Online ISBN: 978-1-4613-2057-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics