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Epidemiology of Ocular Melanoma

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Basic and Clinical Aspects of Malignant Melanoma

Part of the book series: Cancer Treatment and Research ((CTAR,volume 35))

Abstract

Ocular melanomas are eye tumors composed of melanocytic cells with malignant characteristics. Most ocular melanomas arise from uveal melanocytes distributed throughout the stroma of the choroid, ciliary body, and iris; conjuctival melanocytes may also be the cells of origin for melanomas [1]. Since conjunctival and uveal melanocytes share a common embryologic origin with melanocytes of the skin from the neural crest [2], investigators have suggested the possibility of similar etiologies for ocular and cutaneous melanoma [3, 4]. While both melanomas share certain clinical and epidemiologic characteristics, other factors demonstrate no correlation. This issue needs further investigation, as discussed in this review.

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Authors
  1. Leslie Hyman
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  2. M. Cristina Leske
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  3. Anthony P. Polednak
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Editors and Affiliations

  1. School of Medicine, Health Sciences Center, State University of New York at Stony Brook, Stony Brook, New York, USA

    Larry Nathanson M.D. (Professor of Medicine, Director) (Professor of Medicine, Director)

  2. Oncology-Hematology Division, Winthrop University Hospital, Suite 300, 222 Station Place North, Mineola, New York, 11501, USA

    Larry Nathanson M.D. (Professor of Medicine, Director) (Professor of Medicine, Director)

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Hyman, L., Leske, M.C., Polednak, A.P. (1987). Epidemiology of Ocular Melanoma. In: Nathanson, L. (eds) Basic and Clinical Aspects of Malignant Melanoma. Cancer Treatment and Research, vol 35. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2043-2_4

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