Summary of the Pathogenesis of IgA Nephropathy

  • Andrew J. Woodroffe
Part of the Topics in Renal Medicine book series (TIRM, volume 2)


As in so many conditions, the causes of IgA nephropathy and its close relative, Henoch-Schönlein purpura (HSP), remain obscure despite considerable efforts in human and animal experimentation. However, such efforts over the past ten years have taught us something about the mechanisms involved in mesangial IgA nephritis and this chapter reviews this knowledge, paying special tribute to those involved and emphasizing areas that may prove ultimately to be of diagnostic, prognostic, or therapeutic value to patients with IgA nephropathy.


Systemic Lupus Erythematosus Mesangial Deposit Control Peripheral Blood Mononuclear Cell Tonsillar Cell Raji Cell Assay 
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© Martinus Nijhoff Publishing, Boston 1987

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  • Andrew J. Woodroffe

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