Skip to main content

Radical hysterectomy and pelvic lymphadenectomy

  • Chapter
Cervix Cancer

Part of the book series: Cancer Treatment and Research ((CTAR,volume 31))

Abstract

The advent of the twentieth century witnessed the initiation of radical abdominal surgery for the treatment of uterine cancers. Recognizing the pattern of direct infiltrative extension and nodal metastases, Wertheim [1] championed an extirpative procedure that included wide parametrial resections with ureteral mobilization, inclusion of an extended segment of the uterosacral ligaments, and excision of a generous portion of the vagina and sampling of suspicious pelvic nodes. Wertheim’s experience with 500 cases included an operative mortality of 18% which was predominantly attributable to the difficulties in managing postoperative infections. Because of the associated operative mortality and the evolving applications of radiotherapy, enthusiasm for the surgical treatment of cervical carcinoma was nearly dormant for several decades.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Wertheim E. 1912. The extended abdominal operation for carcinoma uteri (based on 500 operative cases). Am J Obstet (NY) 66:169–232.

    Google Scholar 

  2. Meigs JV. 1944. Carcinoma of the cervix-the Wertheim operation. Surg Gynecol Obstet 78:195–199.

    Google Scholar 

  3. Meigs JV. 1951. Radical hysterectomy with bilateral pelvic lymph node dissections. A report of 100 patients operated on five or more years ago. Am J Obstet Gynecol 62:854–865.

    PubMed  CAS  Google Scholar 

  4. Roddick JW Jr, Greenelaw RH. 1971. Treatment of cervical cancer: a randomized study of operation and radiation. Am J Obstet Gynecol 109:754–759.

    PubMed  Google Scholar 

  5. Newton M. 1975. Radical hysterectomy or radiotherapy for stage I cervical cancer: a prospective comparison with 5 and 10 year follow-up. Am J Obstet Gynecol 123:535–539.

    PubMed  CAS  Google Scholar 

  6. Morley GW, Seski JC. 1976. Radical pelvic surgery versus radiation therapy for stage I carcinoma of the cervix (exclusive of microinvasion). Am J Obstet Gynecol 126:785–794.

    PubMed  CAS  Google Scholar 

  7. van Nagell JR Jr, Roddick JW Jr, Lowin DM. 1971. The staging of cervical cancer: inevitable discrepancies between clinical staging and pathologic findings. Am J Obstet Gynecol 110:973–978.

    PubMed  Google Scholar 

  8. Symmonds RE, Pratt JH, Welch JS. 1964. Extended Wertheim operation for primary, recurrent, or suspected recurrent carcinoma of the cervix. Obstet Gynecol 24:15–24.

    PubMed  CAS  Google Scholar 

  9. Webb MJ, Symmonds RE. 1979. Wertheim hysterectomy: a reappraisal. Obstet Gynecol 54:140–145.

    PubMed  CAS  Google Scholar 

  10. Cavanagh D, Rutledge F. 1960. The cervical cone biopsy-hysterectomy sequence and factors affecting the febrile morbidity. Am J Obstet Gynecol 80:53–59.

    PubMed  CAS  Google Scholar 

  11. Malinak LR, Jeffrey RA Jr, Dunn WJ. 1964. The conization-hysterectomy time interval: a clinical and pathologic study. Obstet Gynecol 23:317–329.

    PubMed  CAS  Google Scholar 

  12. Mikuta JJ, Giuntoli RL, Rubin EL, Mangan CE. 1977. The ‘problem’ radical hysterectomy. Am J Obstet Gynecol 128:119–124.

    PubMed  CAS  Google Scholar 

  13. Webb MJ, Symmonds RE. 1979. Radical hysterectomy: influence of recent conization on morbidity and complications. Obstet Gynecol 53:290–292.

    PubMed  CAS  Google Scholar 

  14. McIlrath DC, van Heerden JA, Edis AJ, Dozois RR. 1976. Closure of abdominal incisions with subcutaneous catheters. Surgery 80:411–415.

    PubMed  CAS  Google Scholar 

  15. Symmonds RE, Pratt JH. 1961. Prevention of fistulas and lymphocysts in radical hysterectomy: preliminary report of a new technic. Obstet Gynecol 17:57–64.

    PubMed  CAS  Google Scholar 

  16. Podratz KC, Angerman NS, Symmonds RE. 1982. Complications of ureteral surgery in the nonradiated patient. In: Management of Complications in Gynecologic Oncology. Edited by G Delgado, JP Smith. New York, John Wiley & Sons, pp 113–149.

    Google Scholar 

  17. Boronow RC. 1982. Urologic complications secondary to radiation alone or radiation and surgery. In: Management of Complications in Gynecologic Oncology (G Delgado, JP Smith, eds). John Wiley & Sons, New York, pp 163–197.

    Google Scholar 

  18. Kadar N, Nelson JH Jr. 1984. Treatment of urinary incontinence after radical hysterectomy. Obstet Gynecol 64:400–405.

    PubMed  CAS  Google Scholar 

  19. Martimbeau PW, Kjorstad KE, Iversen T. 1982. Stage IB carcinoma of the cervix, The Norwegian Radium Hospital. II. Results when pelvic nodes are involved. Obstet Gynecol 60:215–218.

    PubMed  CAS  Google Scholar 

  20. Bleker OP, Ketting BW, van Wayjen-Eecen B, Kloosterman GJ. 1983. The significance of microscopic involvement of the parametrium and/or pelvic lymph nodes in cervical cancer Stages IB and IIA. Gynecol Oncol 16:56–62.

    Article  PubMed  CAS  Google Scholar 

  21. Webb MJ, Symmonds RE. 1980. Site of recurrence of cervical cancer after radical hysterectomy. Am J Obstet Gynecol 138:813–817.

    PubMed  CAS  Google Scholar 

  22. Niloff JM, Bast RC Jr, Schaetzl EM, Knapp RC. 1985. Predictive value of CA 125 antigen levels in second-look procedures for ovarian cancer. Am J Obstet Gynecol 151:981–985.

    PubMed  CAS  Google Scholar 

  23. Fuller AF Jr, Elliott N, Kosloff C, Lewis JL Jr. 1982. Lymph node metastases from carcinoma of the cervix, Stages IB and IIA: implications for prognosis and treatment. Gynecol Oncol 13:165–174.

    Article  PubMed  Google Scholar 

  24. Wertheim MS, Hakes TB, Daghestani AN, Nori D, Smith DH, Lewis JL Jr. 1985. A pilot study of adjuvant therapy in patients with cervical cancer at high risk of recurrence after radical hysterectomy and pelvic lymphadenectomy. J Clin Oncol 3:912–916.

    PubMed  CAS  Google Scholar 

  25. Piver MS, Chung WS. 1975. Prognostic significance of cervical lesion size and pelvic node metastases in cervical carcinoma. Obstet Gynecol 46:507–510.

    PubMed  CAS  Google Scholar 

  26. van Nagell JR Jr, Donaldson ES, Parker JC, van Dyke AH, Wood EG. 1977. The prognostic significance of cell type and lesion size in patients with cervical cancer treated by radical surgery. Gynecol Oncol 5:142–151.

    Article  Google Scholar 

  27. Burghardt E, Pickel H. 1978. Local spread and lymph node involvement in cervical cancer. Obstet Gynecol 52:138–145.

    PubMed  CAS  Google Scholar 

  28. van Nagell JR Jr, Rayburn W, Donaldson ES, Hanson M, Gay EC, Yoneda J, Marayuma Y, Powell DF. 1979. Therapeutic implications of patterns of recurrence in cancer of the uterine cervix. Cancer 44:2354–2361.

    Article  PubMed  Google Scholar 

  29. Boyce J, Fruchter RG, Nicastri AD, Ambiavagar P-C, Reinis MS, Nelson JH Jr. 1981. Prognostic factors in Stage I carcinoma of the cervix. Gynecol Oncol 12:154–165.

    Article  PubMed  CAS  Google Scholar 

  30. Gallup DG, Abell MR. 1977. Invasive adenocarcinoma of the uterine cervix. Obstet Gynecol 49:596–603.

    PubMed  CAS  Google Scholar 

  31. Tamimi HK, Figge DC. 1982. Adenocarcinoma of the uterine cervix. Gynecol Oncol 13:335–344.

    Article  PubMed  CAS  Google Scholar 

  32. van Nagell JR Jr, Donaldson ES, Wood EG, Parker JC Jr. 1978. The significance of vascular invasion and lymphocytic infiltration in invasive cervical cancer. Cancer 41:228–234.

    Article  PubMed  Google Scholar 

  33. Barber HRK, Sommers SC, Rotterdam H, Kwon T. 1978. Vascular invasion as a prognostic factor in Stage IB cancer of the cervix. Obstet Gynecol 52:343–348.

    PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1987 Martinus Nijhoff Publishers, Boston

About this chapter

Cite this chapter

Podratz, K.C., Symmonds, R.E. (1987). Radical hysterectomy and pelvic lymphadenectomy. In: Surwit, E.A., Alberts, D.S. (eds) Cervix Cancer. Cancer Treatment and Research, vol 31. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2027-2_6

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-2027-2_6

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9207-4

  • Online ISBN: 978-1-4613-2027-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics