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Cervix Cancer pp 185–197Cite as

Human tumor clonogenic assay studies of cervical cancer

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Part of the book series: Cancer Treatment and Research ((CTAR,volume 31))

Abstract

The interface between laboratory investigation and clinical oncology remains an area of productive discussion between cell biologists and physicians treating malignancies. Researchers in cell biology have developed techniques for cloning human tumor cells, which now permit in vitro studies of fresh human tumors as well as established cell lines. These technical advances have become standardized among laboratories, and a human tumor clonogenic assay (HTCA) now is done on primary human tumors in many centers throughout the world [1–3]. Some types of human tumors have been easier to grow in vitro than others. Specifically, cancers of the ovary [4], lung [5, 6], breast [7, 8], and melanomas [9, 10] have been successfully grown in many laboratories, studying the effects of colony formation following treatment with various cytotoxic drugs.

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Authors
  1. Charles E. Welander
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  2. R. Lamar Parker Jr.
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Editor information

Editors and Affiliations

  1. Gynecologic Oncology, 5245 E. Knight, 85712, Tucson, Arizona, USA

    Earl A. Surwit M.D.

  2. Section of Hematology and Oncology, Department of Internal Medicine 6th Floor Facility, Arizona Health Sciences Center, University of Arizona, 1501 N. Campbell, 85724, Tucson, Arizona, USA

    David S. Alberts M.D.

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© 1987 Martinus Nijhoff Publisher, Boston

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Welander, C.E., Parker, R.L. (1987). Human tumor clonogenic assay studies of cervical cancer. In: Surwit, E.A., Alberts, D.S. (eds) Cervix Cancer. Cancer Treatment and Research, vol 31. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2027-2_12

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  • DOI: https://doi.org/10.1007/978-1-4613-2027-2_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9207-4

  • Online ISBN: 978-1-4613-2027-2

  • eBook Packages: Springer Book Archive

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