Plant Mitochondrial Genes, Cytochrome C Oxidase and Cytoplasmic Male Sterility

  • Malcolm J. Hawkesford
  • Christopher J. Leaver


In the mitochondrial genome of cytoplasmic male sterile plants multiple recombination events have created unique chimaeric genes. These may be expressed as variant polypeptides, in one specific case as a modified form of cytochrome c oxidase subunit 1 polypeptide, and in another as a novel polypeptide apparently associated with this same subunit. Models for the molecular basis of cytoplasmic male sterility are discussed in relation to function and biogenesis of cytochrome c oxidase.


Mitochondrial Genome Cytoplasmic Male Sterility Oxidase Subunit coxI Gene Plant Mitochondrion 
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  1. 1.
    R. Douce, “Mitochondria in Higher Plants”., Academic Press, Orlando (1985).Google Scholar
  2. 2.
    B.L. Ward, R.Anderson and A. J. Bendich. The size of the mitochondrial genome is large and variable in a family of plants (Cucurbitaceae). Cell 25: 793 (1981).Google Scholar
  3. 3.
    D. M. Lonsdale, T. P. Hodge and C. M.-R. Fauron, The physical map and organisation of the mitochondrial genome from the fertile cytoplasm of maize, Nucleic Acids Res. 12: 9249 (1984).CrossRefGoogle Scholar
  4. 4.
    P. G. Isaac, V. P. Jones and C. J. Leaver, The maize cytochrome c oxidase subunit I gene: sequence, expression and rearrangement in cytoplasmic male sterile plants, EMBO J. 4: 1617 (1985).Google Scholar
  5. 5.
    T. D. Fox and C. J. Leaver, The Zea mays mitochondrial gene coding cytochrome oxidase subunit II has an intervening sequence and does not contain TGA codons, Cell 26: 315 (1981).CrossRefGoogle Scholar
  6. 6.
    R. Hiesel, W. Schobel, W. Schuster and A. Brennicke, The cytochrome oxidase subunit I and subunit III genes in Oenothera mitochondria are transcribed from identical promoter sequences, EMBO J. 6: 29 (1987).Google Scholar
  7. 7.
    A. J. Dawson, V. P. Jones and C. J. Leaver, The apocytochrome b gene in maize mitochondria does not contain introns and is preceded by a potential ribosome binding site, EMBO J. 3: 2107 (1984).Google Scholar
  8. 8.
    P. G. Isaac, A. Brennicke, S. M. Dunbar and C. J. Leaver, The mitochondrial genome of fertile maize (Zea mays L.) contains two copies of the gene encoding the alpha-subunit of the F1-ATPase, Curr. Genet. 10: 321 (1985).CrossRefGoogle Scholar
  9. 9.
    R. E. Dewey, C. S. Levings III and D. H. Timothy, Nucleotide sequence of AT Pase subunit 6 gene of maize mitochondria, Plant Physiol. 79: 914 (1985).CrossRefGoogle Scholar
  10. 10.
    R. E. Dewey, A. M. Schuster, C. S. Levings and D. H. Timothy, Nucleotide sequence of FO-ATPase proteolipid (subunit 9) gene of maize mitochondria, Proc. Natl. Acad. Sci. USA 82: 1015 (1985).CrossRefGoogle Scholar
  11. 11.
    D. B. Stern, A. G. Band and W. F. Thompson, The watermelon mitochondrial URF-1 gene: evidence for a complex structure, Curr. Genet. 10: 857 (1986).CrossRefGoogle Scholar
  12. 12.
    A. J. Dawson, T. P. Hodge, P. G. Isaac, C. J. Leaver and D. M. Lonsdale, Location of the genes for cytochrome oxidase subunits I and II, apocytochrome b, alpha—subunit of the F1—AT Pase and the ribosomal RNA genes on the mitochondrial genome of maize (Zea mays L.), Curr. Genet. 10: 561 (1986).CrossRefGoogle Scholar
  13. 13.
    A. J. Dawson, V. P. Jones and C. J. Leaver, Identification and characterisation of higher plant mitochondrial genes. Methods in Enz. 118: 400 (1986).Google Scholar
  14. 14.
    W. Schuster, R. Hiesel, P. G. Isaac, A. Brennicke and C. J. Leaver, Transcript termini of messenger RNA s in higher plant mitochondria, Nucleic Acids Res. 14: 5943 (1986).CrossRefGoogle Scholar
  15. 15.
    E. Hack and C. J. Leaver, The alpha-subunit of the maize F1-AT Pase is synthesised in the mitochondrion, EMBO J. 2: 1783 (1983).Google Scholar
  16. 16.
    E. Hack and C. J. Leaver, Synthesis of a dicyclohexylcarbodiimide-binding proteolipid by cucumber (Cucumissativus L.) mitochondria, Curr. Genet. 8: 537 (1984).CrossRefGoogle Scholar
  17. 17.
    C. J. Leaver and M. W. Gray, Mitochondrial genome organization and expression in higher plants, Ann. Rev. Plant Physiol. 33: 373 (1982).CrossRefGoogle Scholar
  18. 18.
    R. E. Dewey, C. S. Levings and D. H. Timothy, Novel recombinations in the maize mitochondrial genome produce a unique transcriptional unit in the Texas male sterile cytoplasm, Cell 44: 437 (1986).CrossRefGoogle Scholar
  19. 19.
    B. G. Forde and C. J. Leaver, Nuclear and cytoplasmic genes controlling synthesis of variant mitochondrial polypeptides in male-sterile maize, Proc. Natl. Acad. Sci. 77: 418 (1980).CrossRefGoogle Scholar
  20. 20.
    L. K. Dixon and C. J. Leaver, Mitochondrial gene expression and cytoplasmic male sterility in sorghum, Plant Mol. Biol. 1: 89 (1982).Google Scholar
  21. 21.
    J. Bailey-Serres, D. K. Hanson, T. D. Fox and C. J. Leaver, Mitochondrial genome rearrangement leads to extension and relocation of the cytochrome c oxidase subunit I gene in Sorghum, Cell 47: 567 (1986).CrossRefGoogle Scholar
  22. 22.
    P. P. Mueller, M. K. Reif, S. Zonghou, C. Sengstag, T. L. Mason and T. D. Fox, A nuclear mutation that post-transcriptionally blocks accumulation of a yeast mitochondrial gene product can be suppressed by mitochondrial gene rearrangement. J. Mol. Biol. 175: 431 (1984).CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Malcolm J. Hawkesford
    • 1
  • Christopher J. Leaver
  1. 1.Department of BotanyUniversity of EdinburghEdinburghScotland

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