Current Correction Factors Inadequately Predict the Relationship between Transcutaneous (tc) and Arterial PCO2 in Sick Neonates

  • R. J. Martin
  • A. Beoglos
  • M. J. Miller
  • J. M. DiFiore
  • W. A. Carlo
Part of the Advances in Experimental Medicine and Biology book series (ABBI, volume 7)

Summary

Despite widespread tcPCO2 monitoring the relationship between tcPCO2 and PaCO2 remains unclear. It has been assumed that after standard temperature correction, a constant metabolic factor can explain the elevation of tcPCO2 over PaCO2. Our data demonstrate a progressive increase in the difference between temperature corrected tcPCO2 and PaCO2 as PaCO2 increases. Thus a constant metabolic factor cannot account for the elevation of temperature corrected tcPCO2 over PaCO2. We speculate that as PaCO2 rises, CO2 production exceeds removal resulting in a progressive gradient between temperature corrected tcPCO2 and PaCO2.

Keywords

Dioxide Clarification 

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References

  1. 1.
    O. Siggard-Andersen, “The Acid-Base Status of Blood,” Munkgaard, Copenhagen(1976).Google Scholar
  2. 2.
    J. Severinghaus, M. Stafford, and A.F. Bradley, TcPCO2 electrode design, calibration and temperature gradient problems, Acta Anesthesiol Scand (Suppl) 68:118–122 (1978).CrossRefGoogle Scholar
  3. 3.
    T.N. Hansen and W.H. Tooley, Skin surface carbon dioxide tension in sick infants, Pediatrics 64:942–945 (1979).Google Scholar

Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • R. J. Martin
    • 1
  • A. Beoglos
    • 1
  • M. J. Miller
    • 1
  • J. M. DiFiore
    • 1
  • W. A. Carlo
    • 1
  1. 1.Department of PediatricsRainbow Babies and Childrens Hospital Case Western Reserve UniversityClevelandUSA

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