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Compliance of Patients Currently on Study

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Book cover Conducting Clinical Trials

Abstract

Compliance is an important issue in the conduct of research. The quality and eventual value in establishing a drug’s efficacy and side effects depend upon the patient ingesting the medication and undertaking the scheduled evaluations. Bringing patients into the research process as participants in these goals is an excellent beginning. At the practical level, whether or not patients appear for visits, undertake necessary blood tests, or submit required diaries is an undeniable matter of record. Whether the medication dispensed is taken or used is not so easily established. This section considers ways of enhancing patients’ medication taking and visit compliance.

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Further Reading

  • Eraker, S.A., Kirscht, J.P., and Becker, M.H., Understanding and improving patient compliance: A review, Ann. Int. Med. 100:258–268, 1984.

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  • Greenberg, R.N., Overview of patient compliance with medication dosing: A literature review, Clin. Ther. 6:592–599, 1984.

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  • Peto, P., Pike, M.C., Armitage, P., et al. ,Design and analysis of randomized clinical trials requiring prolonged observation of each patient, Br. J. Cancer 34:585–612, 1976.

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© 1987 Plenum Publishing Corporation

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Iber, F.L., Riley, W.A., Murray, P.J. (1987). Compliance of Patients Currently on Study. In: Conducting Clinical Trials. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1919-1_13

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  • DOI: https://doi.org/10.1007/978-1-4613-1919-1_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9067-4

  • Online ISBN: 978-1-4613-1919-1

  • eBook Packages: Springer Book Archive

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