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The Influence of Antibiotics on the Serum Resistance of Enterobacteriaceae

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Antibiosis and Host Immunity

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Abstract

Resistance to the bactericidal activity of serum is an important virulence factor of gram-negative bacteria. This serum resistance is responsible for the ineffectiveness of a main host defense mechanism, the attack and killing by the complement system.

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References

  1. B. S. Dutcher, A. M. Reynard, M. E. Beck and R. K. Cunningham, Potentiation of antibiotic bactericidal activity by normal human serum, Antimicrob. Agents Chemother. 13:820 (1978).

    PubMed  CAS  Google Scholar 

  2. J. Fierer and F. Finley, Lethal effect of complement and lysozyme on polymyxin-treated, serum-resistant gram-negative bacilli, J. Infect. Pis. 140:581 (1979).

    Article  CAS  Google Scholar 

  3. H. Friedman and G. H. Warren, Antibody-mediated bacteriolysis: Enhanced killing of cyclacillin-treated bacteria, Proc. Soc. Exp. Biol. Med. 153:301 (1976).

    PubMed  CAS  Google Scholar 

  4. V. Lorian and B. A. Atkinson, Effect of serum and blood on Enterobacteriaceae grown in the presence of subminimal inhibitory concentrations of ampicillin and mecillinam, Rev. Infect. Pis. 1:797 (1979).

    Article  CAS  Google Scholar 

  5. M. M. Mayer, Complement and complement fixation, in: “Experimental Immunochemistry,” E. A. Kabat and M. M. Mayer, eds., 2nd edition, C. C. Thomas, Springfield (1964).

    Google Scholar 

  6. P. W. Taylor, H. Gaunt and F. M. Unger, Effect of subinhibitory concentrations of mecillinam on the serum susceptibility of Escherichia coli strains, Antimicrob. Agents Chemother. 19:786 (1981).

    PubMed  CAS  Google Scholar 

  7. W. H. Traub and J. C. Sherris, Studies on the interaction between serum bactericidal activity and antibiotics in vitro, Chemotherapy 15:70 (1970).

    Article  PubMed  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Medizinische Mikrobiologie und Immunologie, Ruhr-Universität Bochum, Bochum, Germany

    Christoph Wiemer, Britta Kubens & Wolfgang Opferkuch

Authors
  1. Christoph Wiemer
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  2. Britta Kubens
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  3. Wolfgang Opferkuch
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Editor information

Editors and Affiliations

  1. Departments of Pharmacology and Therapeutics and Internal Medicine, University of South Florida, College of Medicine, 12901 N. 30th Street, Box 9, Tampa, Florida, USA

    Andor Szentivanyi M.D. (University Distinguished Professor) (University Distinguished Professor)

  2. Department of Medical Microbiology and Immunology, University of South Florida, College of Medicine, 12901 N. 30th Street, Box 10, Tampa, Florida, USA

    Herman Friedman Ph.D. (Professor and Chairman) (Professor and Chairman)

  3. Department of Medical Microbiology, Faculty of Medicine, Rhein.-Westfälische Technische Hochschule Aachen, 5100, Aachen, Federal Republic of Germany

    Günther Gillissen M.D., Ph.D. (Professor and Chairman) (Professor and Chairman)

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© 1987 Plenum Press, New York

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Wiemer, C., Kubens, B., Opferkuch, W. (1987). The Influence of Antibiotics on the Serum Resistance of Enterobacteriaceae. In: Szentivanyi, A., Friedman, H., Gillissen, G. (eds) Antibiosis and Host Immunity. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1901-6_10

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  • DOI: https://doi.org/10.1007/978-1-4613-1901-6_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9058-2

  • Online ISBN: 978-1-4613-1901-6

  • eBook Packages: Springer Book Archive

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