Antibodies pp 91-105 | Cite as

Network and Regulation of the Idiotypic Repertoire

  • Carol Victor-Kobrin
  • Zahava Barak
  • F. A. Bonilla
  • Constantin Bona


The emergence and evolution of the immune and idiotypic repertoires of the immune system are closely intertwined, given that idiotypes are after all the antigenic markers of the antibody molecule’s variable region. Those factors which can affect the expression of these two repertoires will differ according to the maturity of the immune system. At this point we would like to distinguish between those forces affecting the primary or early repertoire versus those influencing the expression of the later secondary repertoire.


Germline Gene Light Chain Variable Region Germline Versus Germline Versus Gene Immunogenic Challenge 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Carol Victor-Kobrin
    • 1
  • Zahava Barak
    • 1
  • F. A. Bonilla
    • 1
  • Constantin Bona
    • 1
  1. 1.Department of MicrobiologyMount Sinai School of MedicineNew YorkUSA

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