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Immunological and Genetic Effects

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Ultrasound
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Abstract

The obvious importance of the immunological system in the protection from infection and the role of DNA as the store of genetic information for future generations means that both of these systems have been intensively investigated as potential “targets” for ultrasound interactions. In common with many other areas of biological investigation the majority of the published reports are concerned with the in vitro exposure of isolated cells or even purified macromolecules. This is a reflection of the fact that it is often difficult to obtain a precise measurement of a given vital function in vivo (partly because of the difficulty of access without perturbing the function you are trying to measure and partly because of the inherent homeostatic mechanisms which operate to prevent any change). Consequently, in vitro exposure systems are favoured because they enable more sophisticated and/or quantifiable measurements to be performed.

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References

  • Anderson, D. W. and Barrett, J. T., 1979, Ultrasound: a new immunosuppressant. Clin. Immunol. Immunopathol.. 14: 18.

    Article  PubMed  CAS  Google Scholar 

  • Anderson, D. W. and Barrett, J. T., 1981, Depression of phagocytosis by ultrasound, Ultrasound Med. Biol.. 7: 267.

    CAS  Google Scholar 

  • Child, S. Z., Hare, J. D., Carstensen, E. L., Vives, B., Davis, J., Adler, A. and Davis, H.T., 1981. Test for the effects of diagnostic levels of ultrasound on the immune response of mice, Clin. Immunol. Immunopathol.. 18: 299.

    Article  CAS  Google Scholar 

  • Combes, R. D., 1975, Absence of mutation following ultrasonic treatment of Bacillus subtilis cells and transforming deoxyribonucleic acid, Brit. J. Radiol.. 48: 306.

    Article  PubMed  CAS  Google Scholar 

  • Crowell, J. A., Kusserow, B. K. and Nyborg, W. L., 1977, Functional changes in white cells after microsonation, Ultrasound Med. Biol.. 3: 185.

    Article  PubMed  CAS  Google Scholar 

  • Dyer, H. J., 1972, Structural effects of ultrasound on the cell, In “Interactions of Ultrasound and Biological Tissues”, Eds. J. M. Reid and M. R. Sikov, DHEW Publication 73–8008, (FDA): 73.

    Google Scholar 

  • Ehlinger, C. A., Katayama, P. K., Roester, M. R. and Mattingly, R. F., 1981, Diagnostic ultrasound increases sister chromatid exchange; preliminary report, Wise. Med. J.. 80: 21.

    CAS  Google Scholar 

  • Ford, W. L., Burr, W. and Simonsen, M., 1970, A lymph node weight assay for the grafversus-host activity of rat lymphoid cells, Transplantation. 10: 258.

    Article  PubMed  CAS  Google Scholar 

  • Fung, H., Cheung, K., Lyons, E.A. and Kay, N.E., 1978, The effect of low dose ultrasound on human peripheral lymphocyte function in vitro. In “Ultrasound in Medicine”, Eds. D. N. White and E. A. Lyons, Plenum Press, N.Y., 4: 583.

    Google Scholar 

  • Galperin-Lemaitre, H., Kirsch-Volders, M. and Levi, S., 1975, Ultrasound and mammalian DNA, Lancet. 2: 662.

    Article  PubMed  CAS  Google Scholar 

  • Gebhart, E., 1981, Sister chromatid exchange (SCE) and structural chromosome aberration in mutagenicity testing (review article), Human Genetics. 58: 235.

    Article  PubMed  CAS  Google Scholar 

  • Goss, S. A., 1984, Sister chromatid exchange and ultrasound, J. Ultrasound Med.. 3: 463.

    PubMed  CAS  Google Scholar 

  • Haupt, M., Martin, N., Simpson, J. L., Iqbal, M., Elias, S., Dyere, A. and Sabbagha, R. E., 1981, Ultrasonic induction of sister chromatid exchanges in human lymphocytes, Human Genetics, 39: 221.

    Google Scholar 

  • Kunze-Muhl, E. and Golob, E., 1972, Chromosomenanalysen nach Ultraschalleinwirkung, Humangenetik, 14; 237.

    Article  PubMed  CAS  Google Scholar 

  • Liebeskind, D., Bases, R., Elequin, F., Neubort, S., Leifer, R., GOLDBERG, R. and Koenigsberg, M., 1979a Diagnostic ultrasound: effects on the DNA and growth patterns of animal cells, Radiology, 131: 177.

    PubMed  CAS  Google Scholar 

  • Liebeskind, D., Bases, R., Mendez, F., Elequin, F. and Koenigsberg, M., 1979b, Sister chromatid exchanges in lymphocytes after exposure to diagnostic ultrasound, Science. 205: 1273.

    Article  PubMed  CAS  Google Scholar 

  • Macintosh, I. J. C, Brown, R. C. and Coakley, W. T., 1975, Ultrasound and In vitro chromosome aberrations, Brit. J. Radiol.. 48: 230.

    Article  Google Scholar 

  • Macintosh, I. J. C. and Davey, D. A., 1970, Chromosome aberrations induced by an ultrasonic foetal pulse detector, Brit. Med. J.. 4; 92.

    Article  PubMed  CAS  Google Scholar 

  • Macintosh, I. J. C. and Davey, D. A., 1972, Relationship between intensity of ultrasound and induction of chromosome aberrations. Brit. J. Radiol.. 45: 320.

    Article  PubMed  CAS  Google Scholar 

  • Saad, A.H. and Williams, A.R., 1982, Effects on therapeutic ultrasound on clearance rate of blood borne colloidal particles in vivo. Brit. J. Cancer. 45: 202.

    Google Scholar 

  • Spencer, J. L., 1952, Effects of intense ultrasonic vibrations on Pisum. II. Effects on growth and their inheritance, Growth. 16: 255.

    PubMed  CAS  Google Scholar 

  • Thacker, J., 1973, The possibility of genetic hazard from ultrasonic radiation, Curr. Topics. Rad. RES. P.. 8: 235.

    Google Scholar 

  • Thacker, J., 1974, An assessment of ultrasonic radiation hazard using yeast genetic systems, Brit. J. Radiol.. 47: 130.

    Article  PubMed  CAS  Google Scholar 

  • Wang, S. Y., 1977, Ultrasonic radiation of nucleic acid components, Svmp. Biol. Effects and Characterization of Ultrasound Sources. HEW Publication 78-8048: 196.

    Google Scholar 

  • Wells, P. N. T., 1977, “Biomedical Ultrasonics”, Academic Press, London, N.Y.

    Google Scholar 

  • Williams, A. R., 1983, “Ultrasound: biological effects and potential hazards”, Academic Press, London, N.Y.

    Google Scholar 

  • Williams, A. R., Sykes, S. M., and O’Brien, W. D. J., 1976, Ultrasonic exposure modifies platelet morphology and function in vitro. Ultrasound Med. BioL 2: 311.

    Article  CAS  Google Scholar 

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© 1987 Plenum Press, New York

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Williams, A.R. (1987). Immunological and Genetic Effects. In: Repacholi, M.H., Grandolfo, M., Rindi, A. (eds) Ultrasound. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1811-8_14

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  • DOI: https://doi.org/10.1007/978-1-4613-1811-8_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9013-1

  • Online ISBN: 978-1-4613-1811-8

  • eBook Packages: Springer Book Archive

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