T-Lymphocyte Subsets and Schizophrenia

  • Charles A. Kaufmann
  • Lynn E. DeLisi
  • E. Fuller Torrey
  • Susan E. Folstein
  • William J. Smith


Viruses have long been sought as possible etiologic agents in several neurological and psychiatric disorders of unknown etiology such as amyotrophic lateral sclerosis (Zil’ber et al., 1963), multiple sclerosis (Marie, 1884), Parkinson’s disease (von Economo, 1931; Marttila et al., 1981), and schizophrenia (Menninger, 1922). In schizophrenia, evidence for a pathogenic role for viruses, especially those of the genus Herpesvirus, has primarily been indirect and has included behavioral, neuropathological, and most importantly immunological abnormalities (reviewed by Kaufmann et al., 1984).


Multiple Sclerosis Amyotrophic Lateral Sclerosis Schizophrenic Patient Immune Dysregulation Mitogen Response 
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Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • Charles A. Kaufmann
    • 1
  • Lynn E. DeLisi
    • 2
  • E. Fuller Torrey
    • 1
  • Susan E. Folstein
    • 3
  • William J. Smith
    • 4
  1. 1.Neuropsychiatry Branch, Intramural Research ProgramNational Institute of Mental Health, Saint Elizabeth’s HospitalUSA
  2. 2.Clinical Neurogenetics Branch, Intramural Research ProgramNational Institute of Mental HealthBethesdaUSA
  3. 3.Department of PsychiatryThe Johns Hopkins UniversityBaltimoreUSA
  4. 4.Department of SurgeryThe Johns Hopkins UniversityBaltimoreUSA

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