Abstract
As technical details and acid secretory consequences of the various operative procedures for peptic ulcer disease became better understood in the 1950s and 1960s, greater emphasis was placed on determining the incidence of dumping and other long-term sequelae of peptic ulcer surgery. The frequency of various syndromes occurring after gastrectomy and/or vagotomy ranged from practically none to uniform occurrence. These figures were used to support employment of one operation over others, but agreement was far from uniform. However, it remained for the Leeds/ York prospective study, published in 1968, to put the problem in proper perspective.1 As the incidence of sequelae related to removal or destruction or bypass of the pylorus and vagotomy became better appreciated, interest in the 1970s gravitated toward proximal gastric (or highly selective) vagotomy. This acid-reducing operation could safely permit leaving the pylorus intact.
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© 1986 Plenum Publishing Corporation
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Fromm, D. (1986). Peptic Ulcer Disease. In: Thomson, A.B.R., DaCosta, L.R., Watson, W.C. (eds) Modern Concepts in Gastroenterology. Topics in Gastroenterology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1789-0_2
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DOI: https://doi.org/10.1007/978-1-4613-1789-0_2
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