Abstract
Early techniques for estimation of right ventricular volumes and systolic performance employed indicator-dilution concepts, with injection of dye, cold saline, or radiotracer into the right ventricle and analysis of the downstream washout curve {1–3}. These techniques fell into disuse with the development of imaging methods which permitted more direct quantitation of relative and absolute right ventricular volumes. Contrast ventriculography, radionuclide ventriculography, and echocardiography have all been employed for analysis of right ventricular volumes and function. More recently developed imaging modalities, such as rapid computerized tomography and gated magnetic resonance imaging {4} (Figure 1–1) offer potential advantages for optimally delineating right ventricular anatomy and function. These techniques provide features such as improved image resolution and the feasibility of image reconstruction in a variety of imaging planes which may be particularly useful in defining the complex structure of the right ventricular cavity. The discussion in this chapter will be directed predominantly to presently conventional imaging methods: contrast ventriculography, radionuclide ventriculography, and echocardiography.
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References
Freis ED, Rivara GL, Gilmonre BL: Estimation of residual and end-diastolic volumes of the right ventricle of men without heart disease, using the dye-dilution method. Am Heart J 60: 898, 1960.
Lewis ML, Giuntini C, Donato L, Harvey RM, Cournand A: Quantitative radiocardiography. III. Results and validation of theory and method. Circulation 26: 189, 1962.
Rapaport E, Wong M, Ferguson RE, Bernstein P, Wiegand BD: Right ventricular volumes in patients with and without heart failure. Circulation 31: 531–541, 1965.
Byrd BF, Schiller NB, Botvinick EH, Higgins CB: Normal cardiac dimensions by magnetic resonance imaging. Am J Cardiol 55: 1440 1442, 1985.
Reedy T, Chapman CB: Measurement of right ventricular volume by cineangioflurography. Amer Heart J 66: 221, 1963.
Goerke RJ, Carlsson E: Calculation of right and left cardiac volumes. Invest Radiol 2: 360, 1967.
Arcilla R, Tsai P, Thilenius O, Ranniger K: Angiographic method for volume estimation of right and left ventricles. Chest 60: 446, 1971.
Ferlinz J, Gorlin R, Cohn PF, Herman MV: Right ventricular performance in patients with coronary artery disease. Circulation 52: 608–615, 1975.
Fisher EA, DuBrow IW, Hastreiter AR: Right ventricular volume in congenital heart disease. Am J Cardiol 36: 67–75, 1975.
Gentzler RD, Briselli MF, Gault JH: Angiographic estimation of right ventricular volume in man. Circulation 50: 324–330, 1974.
Graham TP, Jarmakani JM, Atwood GF, Canent RV: Right ventricular volume determinations in children: Normal values and observations with volume or pressure overload. Circulation 47: 144–153. 1973.
Horn V, Mullins CB, Saffer SI, Jones DC, Freeborn WA, Knapp RS, Nixon JV: A comparison of mathematical models for estimating right ventricular volumes in animals and man. Clin Cardiol 2: 341–347, 1979.
Lange PE, Budach W, Radtke W, Onnasch DGW, Heintzen PH: Right ventricular imaging with digital subtraction angiocardiography using intraventricular contrast injection. Am J Cardiol 54: 839–842, 1984.
Steele P, Kirch D, LeFree M, Battock D: Measurement of right and left ventricular ejection fractions by radionuclide angiocardiography in coronary artery disease. Chest 70: 51, 1976.
Berger HJ, Matthay RA, Loke J, Marshall RC, Gottschalk A, Zaret BL: Cardiac performance with quantitative radionuclide angiocardiography: Right ventricular ejection fraction with reference to findings in chronic obstructive pulmonary disease. Am J Cardiol 41: 897–905, 1978.
Reduto LA, Berger HJ, Cohen LS, Gottschalk A, Zaret BL: Sequential radionuclide assessment of left and right ventricular performance after acute transmural myocardial infarction. Ann Int Med 89: 441–448, 1978.
Tobinick E, Schelbert HR, Henning H, LeWinter M, Taylor A, Ashburn WL, Karliner JS: Right ventricular ejection fraction in patients with acute anterior and inferior myocardial infarction assessed by radionuclide angiography. Circulation 57: 1078–1084, 1978.
Winzelberg GC, Boucher CA, Pohost GM, McKusick KA, Bingham JB, Okada RD, Strauss HW: Right ventricular function in aortic and mitral valve disease. Chest 79: 520–528, 1981.
Maddahi J, Berman DS, Matsuoka DT, Waxman AD, Stankus KE, Forrester JS, et al: A new technique for assessing right ventricular ejection fraction using rapid multiple-gated equilibrium cardiac blood pool scintigraphy. Circulation 60: 581–589, 1979.
Holman BL, Wynne J, Zielonka JS, Idoine JD: A simplified technique for measuring right ventricular ejection fraction using the equilibrium radionuclide angiocardiogram and the slant-hole collimator. Radiology 138: 429–435, 1981.
Konstam MA, Kahn PC, Curran BH, Idoine J, Wynne J, Holman, BL: Accoracy of equilibrium (gated) radionuclide ejection fraction measurement in the pressure or volume overloaded right ventricle. Chest 86: 681–687, 1984.
Knapp WH, Helas F, Lambrecht RM, et al: Krypton-81m for determination of right ventricular ejection fraction. Eur J Nucl Med 5: 487–492, 1980.
Ham HR, Piepz A, Vandevivere J, et al: The evaluation of right ventricular performance using krypton-81m. Clin Nucl Med 8: 257–260, 1983.
Sugrue DD, Kamal S, Deanfield JE, McKenna WI, et al: Assessment of right ventricular function and anatomy using peripheral vein infusion of krypton-81 m. Br J Radiol 56: 657–663, 1983.
Nienaber CA, Speilmann RP, Wasmus G, Mathey DG, Montz R, Bleifeld: Clinical use of ultrasound-lived radionuclide krypton-81m for noninvasive analysis of right ventricular performance in normal subjects and patients with right ventricular dysfunction. JACC 5: 687, 1985.
Horn M, Witztum K, Neveu C, et al: Kr-81m imaging of the right ventricle. J Nucl Med 26, 33–36, 1985.
Wong DF, Natarajan TK, Summer W, Tibbits PA, Beck T, Koller D, Kasecamp W, Lamb J, Olynyk J, Philp MS, Bryan M, Wagner HN: Right ventricular ejection fraction measured by first-pass intravenous krypton-81m: Reproducibility and comparison with technetium-99m. AmJ Cardiol 56: 776–780, 1985.
Wackers FJ, Giles RW, Hoffer PB, Lange RC, Berger HJ, Zaret BL: Gold-195m, a new generator produced short-lived radionuclide for sequential assessment of ventricular performance by first pass radionuclide angiography. Am J Cardiol 50: 89–94, 1982.
Mena I, Narahara KA, DeJong R, Maublant J: Gold-195m, an ultra short-lived generator-produced radionuclide: Clinical application in sequential first pass ventriculography. J Nucl Med 24: 139–144, 1983.
Dymond DS, Elliot AT, Flatman W, et al: The clinical validation of gold-195m: a new short half-life radiopharmaceutical for rapid, sequential, first pass angiocardiography in patients. J Am Coll Cardiol 2: 85–92, 1983.
Fazio F, Gerundini P, Margonata A, et al: Quantitative radionuclide angiocardiography using gold-195m. AmJ Cardiol 53: 1442–1446, 1984.
Treves S, Kulprathipanja S, Hnatowch DJ: Angiocardiography with iridium-191m: An ultra short-lived radionuclide (T1/2 4.9 sec). Circulation 54: 275–279, 1976.
Heller GV, Treves T, Parker A, Duke LA, O’Brien GM, Davis RT, Fitzgibbon C, Packard AB: Comparison of ultrasound-lived iridium-191m with technetium-99m for first pass radionuclide angiocardiographic evaluation of right and left ventricular function in adults. JACC 7: 1295–1302, 1986.
Dehmer GJ, Firth BG, Hillis LD, Nicod P, Willerson JT, Lewis SE: Nongeometric determination of right ventricular volumes from equilibrium blood pool scans: AmJ Cardiol 49: 78–84, 1982.
Korr KS, Gandsman EJ, Winkler ML, Shulman RS, Bough EW: Hemodynamic correlates of right ventricular ejection fraction measured with gated radionuclide angiography. AmJ Cardiol 49: 71–77, 1982.
Hooper W, Horn M, Moser K, Neveu C, Costello D, Bhargava V, Taylor A, Slutsky R: Right ventricular size and function: The discrepancy between cardiac blood pool imaging techniques. Cath and Cardiov Diag 8: 597–606, 1982.
Konstam MA, Idoine J, Wynne J, Grossman W, Cohn L, Beck JR, Kozlowski J, Holman BL: Right ventricular function in pulmonary hypertensive adults with and without atrial septal defects. AmJ Cardiol 51: 1144–8, 1983.
Dell’Italia LJ, Starling MR, Walsh RA, Badke FR, Lasher JC, Blumhardt R: Validation of attenuation-corrected equilibrium radionuclide angiographie determinations of right ventricular volume: Comparison with cast-validated biplane cineventriculography. Circulation 72: 317–326, 1985.
Feigenbaum H: Echocardiography (ed 4 ). Philadelphia, Lea & Febiger, 1986.
Baker BJ, Scovil JA, Kane JJ, Murphy ML: Echocardioraphic detection of right ventricular hypertrophy. Am Heart} 105: 611, 1983.
Bommer W, Weinert L, Neumann A, et al: Determination of right atrial and right ventricular size by two dimensional echocardiography. Circulation 60: 91, 1979.
Panidis IP, et al: Two dimensional echocardiographic estimation of right ventricular ejection fraction in patients with coronary artery disease. J Am Coll Cardiol 2: 911, 1983.
Silverman NH, Hudson S: Evaluation of right ventricular volume and ejection fraction in children by two dimensional echoardiography. Pediatr Cardiol 4: 197, 1983.
Levine RA, Gibson TC, Aretz T, et al: Echo-cardiographic measurement of right ventricular volume. Circulation 69: 497, 1984.
Kaul S, Tei C, Hopkins JM, Shah PM: Assessment of right ventricular function using two dimensional echocardiography. Am Heart} 107: 526, 1984.
Sharling MR, Crawford MH, Sorensen SG, O’Rourke: A new two dimensional echocardiographic technique for evaluating right ventricular size and performance in patients with obstructive lung disease. Circulation 66: 612, 1982.
Yock PG, Popp RL: Noninvasive estimation of right ventricular systolic pressure by Doppler ultrasound in tricuspid regurgitation. Circulation 70: 657, 1984.
Brent BN, Berger HJ, Matthay RA, Mahler D, Pytlik L, Zaret BL: Physiologic correlates of right ventricular ejection fraction in chronic obstructive pulmonary disease: A combined radionuclide and hemodynamic study. Am JCardiol 50:255–262, 1982.
Iskandrian AS, Hakki AH, Ren BF, Kotler MN, Mintz GS, Ross J, Kane SA: Correlation among right ventricular preload, afterload and ejection fraction in mitral valve disease: Radionuclide, echocardiographic and hemodynamic evaluation. JACC 6: 1403–1411, 1984.
Morrison D, Goldman S, Wright AL, Henry R, Sorenson S, Caldwell J, Ritchie J: The effect of pulmonary hypertension on systolic function of the right ventricle. Chest 84: 248–257, 1983.
Coma-Canella I, Lopez-Sendon J: Ventricular compliance in ischemic right ventricular dysfunction. Am J Cardiol. 45: 555–561, 1980.
Friedman BJ, Lozner EC, Curfman GD, Herzberg D, Rolett EL: Characterization of the human right ventricular pressure-volume relation: Effect of dobutamine and right coronary artery stenosis. JACC 4: 999–1005, 1984.
Johnson LL, McCarthy DM, Sciacca R, Cannon PJ: Right ventricular ejection fraction during exercise in patients with coronary artery disease. Circulation 60: 1284, 1979.
Maddahi J, Berman DS, Matsuoka DT, Waxman AD, Forrester JS, Swan HJ: Right ventricular ejection fraction during exercise in normal subjects and in coronary artery disease patients: Assessment by multiplegated equilibrium scintigraphy. Circulation 62: 133, 1980.
Brown KA, Okada RD, Boucher CA, Strauss HW, Pohost GM: Right ventricular ejection fraction response to exercise in patients with coronary artery disease: Influence of both right coronary artery disease and exercise-induced changes in right ventricular afterload. JACC 3: 895–901, 1984.
Cohen M, Horowitz, Machac J, Mindich BP, Fuster V: Response of the right ventricle to exercise in isolated mitral stenosis. AmJ Cardiol 55: 1054–58, 1985.
Matthay RA, Berger HJ, Davies RA, Loke J, Mahler DA, Gottschalk A, Zaret BL: Right and left ventricular exercise performance in chronic obstructive pulmonary disease: Radionuclide assessment. Ann Int Med 93: 234, 1980.
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Konstam, M.A., Pandian, N. (1988). Assessment of Right Ventricular Function. In: Konstam, M.A., Isner, J.M. (eds) The Right Ventricle. Developments in Cardiovascular Medicine, vol 83. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1773-9_1
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DOI: https://doi.org/10.1007/978-1-4613-1773-9_1
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