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Myoepithelial and Endocrine Differentiation in Breast Carcinoma

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Breast Cancer: Scientific and Clinical Progress

Part of the book series: Developments in Oncology ((DION,volume 56))

Abstract

Breast carcinomas are known to express structural features and to show antigenic properties of the luminal secretory cells. Besides well known histocytological patterns, such as gland formation, presence of microvilli and evidence of secretory activity, this conclusion is supported by immunocytochemical and functional studies. Most human breast carcinomas express glycoproteins such as the Epithelial Membrane Antigen and related antigenic fragments (1), cytoskeletal components (signatedly the cytokeratins 18 and 19) (2, 3) and hormonal receptors (4), also expressed by the normal luminal cells of breast ducts and ductules.

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References

  1. Gero, E.J., Hageman, Ph., Schol, D., Sugar, J. and Hilgers, J. Proceedings Biennial International Breast Cancer Research Conference, London, 1985.

    Google Scholar 

  2. Bartek, J., Durban, E.M., Hallowes, R.C. and Taylor-Papadimitriou, J. J. Cell Sci. 75:17–33, 1985.

    PubMed  CAS  Google Scholar 

  3. Altmannsberger, M., Dirk, T., Droese, M., Weber, K. and Osborn, M. Virchows Arch. (Cell Pathol.) 51:265–275, 1986.

    Article  CAS  Google Scholar 

  4. King, W.J. and Greene, G.L. Nature 307:745–747, 1984.

    Article  PubMed  CAS  Google Scholar 

  5. Hamperl, H. Curr. Top. Pathol. 53 161–220, 1970.

    PubMed  CAS  Google Scholar 

  6. Linzell, J.L. J. Physiol. 130:257–267, 1955.

    PubMed  CAS  Google Scholar 

  7. Pinkstaff, C.A. Int. Rev. Cytol. 63:141–261, 1980.

    Article  PubMed  CAS  Google Scholar 

  8. Warburton, M.J., Ferns, S.A. and Rudland, P.S. Exp. Cell Res. 137:373–380, 1982.

    Article  PubMed  CAS  Google Scholar 

  9. Rudland, P.S., Gusterson, B.A., Hughes, CM, Ormerod, E.J. and Warburton, M.J. Cancer Res. 42:5196–5208, 1982.

    PubMed  CAS  Google Scholar 

  10. Hume, W.J. In: Stem Cells. Their identification and characterization (Ed. CS. Potten), Churchill Livingstone, Edinburg, London, Melbourne, New York, 1983, pp. 233–250.

    Google Scholar 

  11. Steelm CG. and Stephens, T.C In: Stem Cells. Their identification and characterization (Ed. CS. Potten), Churchill Livingstone, Edinburg, London, Melbourne, New York, 1983, pp. 275–293.

    Google Scholar 

  12. Putchler, H., Waldrop, F.S., Carter, M.G. and Valentine, L.S. Histochemistry 40:281–289, 1974.

    Article  Google Scholar 

  13. Bussolati, G., Alfani, V., Weber, K. and Osborn, M. J. Histochem. Cytochem. 28:169–173, 1980.

    Article  PubMed  CAS  Google Scholar 

  14. Gusterson, B.A., Warburton, M.J., Mitchell, D., Ellison, M., Neville, M. and Rudland P.S. Cancer Res. 42:4763–4770, 1982.

    PubMed  CAS  Google Scholar 

  15. Vandekerckove, J and Weber, K. J. Mol. Biol. 126:783–802, 1978.

    Article  Google Scholar 

  16. Bussolati, G., Botta, G. and Gugliotta, P. Wirchows Arch. (Cell Pathol.) 34:251–259, 1980.

    Article  CAS  Google Scholar 

  17. Bussolati, C, Gugliotta, P. and Fulcheri, E. In: Advances in Immunohistochemistry (Ed. R.A. De Lellis), Masson, New York, 1984, Chapt. 19, pp. 325–441.

    Google Scholar 

  18. Gown, A.M., Vogel, A.M., Gordon, D. and Lu, P.L. J. Cell Biol. 100:807–813, 1985.

    Article  PubMed  CAS  Google Scholar 

  19. Skalli, O., Ropraz, P., Tzeciak, A., Benzoname, G., Gillssen, D. and Gabbiani, G. J. Cell. Biol., 1987, in press.

    Google Scholar 

  20. Franke, W.W., Schmid, E., Freudenstein, C, Appelhans, B, Osborn, M., Weber, K and Keenan, T.W. J. Cell Biol. 84:633–654, 1980.

    Article  PubMed  CAS  Google Scholar 

  21. Dairkee, S.H., Biayney, C, Smith, H.S. and Hackett, A.J. Proc. Natl. Acad. Sci. USA 82:7409–7413, 1983.

    Article  Google Scholar 

  22. Caselitz, J., Walther, B, Wustrow, J., Scifert, G., Weber, K and Osborn, M. Virchows Arch. (Pathol. Anat.) 409:725–738, 1986.

    Article  CAS  Google Scholar 

  23. Dulbecco, R., Ross Allen, W., Bologna, M. and Bowman, M. Cancer Res. 46:2449–2456, 1986.

    PubMed  CAS  Google Scholar 

  24. Schüren, W., Potvin, C and Seemayer, T.A. Ultrastruct. Pathol. 8:1–11, 1985.

    Article  Google Scholar 

  25. Thorner, P.S., Kahn, H.J., Baumal, R., Lee, K and Moffatt, W. Cancer 57:745–750, 1986.

    Article  PubMed  CAS  Google Scholar 

  26. Eusebi, V., Casadei, G.P., Bussolati, G. and Azzopardi, J.G. Histopathology 1987, in press.

    Google Scholar 

  27. Anthony, P.P. and James, P.D. J. Clin. Pathol. 28:647–655, 1975.

    Article  CAS  Google Scholar 

  28. Pulley, L.T. Am. J. Vet. Res. 34:1513–1522, 1973.

    PubMed  CAS  Google Scholar 

  29. Frese, K. Verh. Dtsch. Ges. Path. 69:152–170, 1985.

    CAS  Google Scholar 

  30. Murad, T.M. and von Haam, H. Cancer Res. 32:1404–1415, 1979.

    Google Scholar 

  31. Cohle, S.D., Tschen, J.A., Smith, F.E., Lane, M. and McGravan, M.H. Cancer 43:2370–2376, 1979.

    Article  PubMed  CAS  Google Scholar 

  32. Seppälä, M. and Wahlström, T. Int. J. Cancer 26:267–268, 1980.

    Article  PubMed  Google Scholar 

  33. Cubilla, A.L. and Woodruff, J.M. Am. J. Surg. Pathol. 4:283–292, 1977.

    Article  Google Scholar 

  34. Fisher, E.R., Palekar, A.S. and N.S.A.B.P. Collaborators. Am. J. Clin. Pathol. 72:909–916, 1979.

    PubMed  CAS  Google Scholar 

  35. Capella, C, Eusebi, V., Mann, B. and Azzopardi, J.G. Histopathology 4:613–630, 1980.

    Article  PubMed  CAS  Google Scholar 

  36. Portanen, S. and Syrjänen, K. Virchows Arch. (Pathol. Anat.) 319:45–51, 1981.

    Article  Google Scholar 

  37. Taxy, J.B, Tischler, A.S., Insalaco, S.J. and Battifora H. Hum. Pathol. 12:170–179, 1981.

    Article  PubMed  CAS  Google Scholar 

  38. Toyoshima, S. Cancer 52:2129–2138, 1983.

    Article  PubMed  CAS  Google Scholar 

  39. Grimelius, L. Acta Soc. Med. Upsala 73:243–270, 1968.

    CAS  Google Scholar 

  40. Azzopardi, J.G., Muretto, P., Goddeeris, P., Eusebi, V. and Lauweryns, J.M. Histopathology 6:549–569, 1982.

    Article  PubMed  CAS  Google Scholar 

  41. Anderson, T.J., Battersby, S. and Ferguson, D.J.P. Histopathology 9:1247–1249, 1985.

    Article  PubMed  CAS  Google Scholar 

  42. Monaghan, P. and Roberts, J.D.B. J. Pathol. 147:281–289, 1985.

    Article  PubMed  CAS  Google Scholar 

  43. Nesland, J.M., Memoli, V.A., Holm, R., Gould, V.E. and Joannessen, J.V. Ultrastruct. Pathol. 8:225–240, 1985.

    Article  PubMed  CAS  Google Scholar 

  44. Nesland, J.M., Holm, R., Joannessen, J.V. and Gould, V.E. J. Pathol. 148:35–43, 1986.

    Article  PubMed  CAS  Google Scholar 

  45. Haimoto, H., Takahashi, Y., Koshikawa, T., Nagura, H. and Kato, K. Lab. Invest. 52:257–263, 1985.

    PubMed  CAS  Google Scholar 

  46. Vinores, S.A., Bonnin, J.M., Rubenstein, L.J. and Marangos, P.J. Arch. Pathol. Lab. Med. 108:536–540, 1984.

    PubMed  CAS  Google Scholar 

  47. Bussolati, G., Papotti, M., Sapino, A., Gugliotta, P., Ghiringhello, B and Azzopardi, J.G. Am. J. Surg. Pathol. 1987, in press.

    Google Scholar 

  48. Wilson, M.J. and Lloyd, R.V. Am. J. Pathol. 115:458–468, 1984.

    PubMed  CAS  Google Scholar 

  49. Riddel, K., Tippens, B.S. and Gown, A.M. Intern. Acad. Pathology Meeting Chicago, March 1987.

    Google Scholar 

  50. Bussolati, G., Gugliotta, P., Sapino, A., Eusebi, V. and Lloyd R.V. Am. J. Pathol. 120:186–192, 1985.

    CAS  Google Scholar 

  51. Cross, A.S., Azzopardi, J.G., Krausz, T., van Noorden, S. and Polak, J.M. Histopathology 9:21–37, 1985.

    PubMed  CAS  Google Scholar 

  52. DeLellis, R.A., Tischler, A.S. and Wolf, H.J. J. Histochem. Cytochem. 32:899–904, 1984.

    Article  CAS  Google Scholar 

  53. Imai, S., Sekiya, N., Marimoto, J., Kiyozuta, Y., Tsubura, Y. and Sakamoto, G. Acta Pathol. Jpn. 36:1319–1326, 1986.

    PubMed  CAS  Google Scholar 

  54. Dempsey, P.J., De Kretser, T.A., Brown, R.W., Whitehead, R.H. and Jose, D.G. Int. J. Cancer 37:857–866, 1986.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Biomedical Sciences and Human Oncology, Section of Pathological Anatomy and Histology, University of Turin, 10126, Torino, Italy

    G. Bussolati, M. Papotti, A. Sapino, P. Gugliotta & L. Macri’

Authors
  1. G. Bussolati
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  2. M. Papotti
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  3. A. Sapino
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  4. P. Gugliotta
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  5. L. Macri’
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Editor information

Editors and Affiliations

  1. AMC Cancer Research Center, Denver, CO, 80214, USA

    Marvin A. Rich  & Jean C. Hager  & 

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© 1988 Kluwer Academic Publishers, Boston

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Bussolati, G., Papotti, M., Sapino, A., Gugliotta, P., Macri’, L. (1988). Myoepithelial and Endocrine Differentiation in Breast Carcinoma. In: Rich, M.A., Hager, J.C., Lopez, D.M. (eds) Breast Cancer: Scientific and Clinical Progress. Developments in Oncology, vol 56. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1753-1_11

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  • DOI: https://doi.org/10.1007/978-1-4613-1753-1_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8984-5

  • Online ISBN: 978-1-4613-1753-1

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