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Vaccinia virus oncolysates in the treatment of malignant melanoma

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Book cover Malignant Melanoma: Biology, Diagnosis, and Therapy

Part of the book series: Cancer Treatment and Research ((CTAR,volume 43))

Abstract

Melanoma is undoubtedly the most extensively studied human malignancy from the standpoint of both immunobiological analysis of the tumor and immunotherapeutic approaches to the disease [1–4]. The reasons for this degree of immunological interest in melanoma include (1) the frequency of spontaneous regressions, which are felt to involve host immune mechanisms [5]; (2) the prognostic significance of lymphoid infiltration of lesions [6]; (3) the demonstration of both antibody and cell-mediated antimelanoma responses in untreated melanoma patients [7]; and (4) the plethora of melanoma-associated antigens that have been documented [8, 9].

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Authors
  1. Jerry A. Bash
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  2. Marc K. Wallack
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Editors and Affiliations

  1. Winthrop-University Hospital, Mineola, New York, USA

    Larry Nathanson

  2. Department of Medicine, Health Science Center, SUNY, Stony Brook, New York, USA

    Larry Nathanson

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© 1988 Kluwer Academic Publishers, Boston

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Bash, J.A., Wallack, M.K. (1988). Vaccinia virus oncolysates in the treatment of malignant melanoma. In: Nathanson, L. (eds) Malignant Melanoma: Biology, Diagnosis, and Therapy. Cancer Treatment and Research, vol 43. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1751-7_11

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  • DOI: https://doi.org/10.1007/978-1-4613-1751-7_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8983-8

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