Advertisement

Do Free Radicals Contribute to the Genesis of Reperfusion-Induced Arrhythmias?

  • Allan S. Manning
  • Renata Crome
Chapter
  • 45 Downloads
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 86)

Abstract

It is now well established that occlusion of a major coronary artery for a relatively short duration, followed by abrupt reperfusion can lead to severe ventricular arrhythmias (see Figure 1).

Keywords

Free Radical Electron Spin Resonance Free Radical Scavenger Xanthine Oxidase Free Radical Production 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Tennant, R. and Wiggers, C.J. Am. J. Physiol. 12: 351–361 (1985).Google Scholar
  2. 2.
    Manning, A.S. and Hearse, D.J. J. Mol. Cell. Cardiol. 16: 497–518 (1984).PubMedCrossRefGoogle Scholar
  3. 3.
    Carbonin, P., Gennaro, M., di Valle, R., and A.M. Weisz. Am. J. Physiol. 240: H730-H737 (1981).PubMedGoogle Scholar
  4. 4.
    Petropoulos, P. and Maijne, N.G. Am. Heart J. 68: 370–382 (1964).PubMedCrossRefGoogle Scholar
  5. 5.
    Sheehan, F.H. and Epstein, S.E. Circulation 65: 259–264 (1982).PubMedCrossRefGoogle Scholar
  6. 6.
    Corr, P.B. and Witkowski, F.X. Circulation 68: Suppl. 1, 16–24 (1983).Google Scholar
  7. 7.
    Araki, H.J., Koiwaya, Y., Nakagaki, and Nakamura, M. Circulation 67: 995–1000 (1983).PubMedCrossRefGoogle Scholar
  8. 8.
    Previtali, M., Klersky, C. and Salerno, J.A. Am. J. Cardiol. 52: 19–25 (1983).PubMedCrossRefGoogle Scholar
  9. 9.
    Markis, J.E., Malagold, M., Parker, J.A., Silverman, K.J. and Barry, W.H. N. Engl. J. Med. 305: 777–782 (1981).PubMedCrossRefGoogle Scholar
  10. 10.
    Mathey, D.G., Kuck, K.H., Tilsner, V., Krebber, H.J. and Bleifeld, W. Circulation 63: 489–497 (1981)PubMedCrossRefGoogle Scholar
  11. 11.
    Reduto, L.A., Smalling, R.W., Freund, G.C. and Freund, K.L. Am. J. Cardiol. 48: 403–409 (1981).PubMedCrossRefGoogle Scholar
  12. 12.
    Rentrop, P., Blanke, P., Karsh, K.R., Kaiser, H., Kostering, H. and Leitz, K. Circulation 63: 307–317 (1981).PubMedCrossRefGoogle Scholar
  13. 13.
    Goldberg, S., Greenspon, A.J., Urban, P.L., Muza, B., Berger, P., Walinsky, P., Maroko, P.R. Am. Heart J. 105: 26–32 (1983).PubMedCrossRefGoogle Scholar
  14. 14.
    Rao, P.S., Cohen, M.V. and Mueller, H.S. J. Mol. Cell Cardiol. 15: 713–716 (1983).PubMedCrossRefGoogle Scholar
  15. 15.
    Gaudel, Y. and Duvelleroy, M.A.. J. Mol. Cell Cardiol. 16: 459–70 (1984).CrossRefGoogle Scholar
  16. 16.
    Cahn, J., Angignard, J., Weber, S. and Lebeau, M. Recent Adv. Cardiac Arr. 1: 30–35 (1983).Google Scholar
  17. 17.
    Barsacchi, R., Pelosi, G., Camici, P., Bonaldo, L., Maiorino, M. and Ursini, F. Biochim. Biophys. Acta 804: 356–360 (1984).PubMedCrossRefGoogle Scholar
  18. 18.
    Woodward, B. and Zakaria, M.N.M. J. Mol. Cell Cardiol. 17: 485–93 (1985).PubMedCrossRefGoogle Scholar
  19. 19.
    Zweier, J.L., Flaherty, J.T. and Weisfeldt, M.L. Proc. Natl. Acad. Sci. 84: 1404–1407 (1987).PubMedCentralPubMedCrossRefGoogle Scholar
  20. 20.
    Garlick, P.B., Davies, M.J., Slater, T.S. and Hearse, D.J. Circulation 74 (Suppl. II): 1393 (Abstract) (1986).Google Scholar
  21. 21.
    Del Maestro, R.F. Acta. Physiol. Scand. (Suppl.) 492: 153–168 (1980).Google Scholar
  22. 22.
    Schultz, G. and Jakobs, K.H.. In: Catecholamines and the Heart (Delius, W., Gerlach, E., Grobecker, H. and Kubler, W., eds.), PP 107–117, Springer-Verlag, Berlin, Heidelberg, New York (1981).CrossRefGoogle Scholar
  23. 23.
    Meerson, F.Z., Kagan, V.E., Kozlov, Y.P., Belkina, L.M. and Arkhipenko, Y.V. Basic Res. Cardiol. 77: 465–485 (1982).PubMedCrossRefGoogle Scholar
  24. 24.
    Clusin, W.T., Bristow, M.R., Karaguezian, H.S., Katzung, B.G. and Schroeder, J.S. Am. J. Cardiol. 49: 606–612 (1982).PubMedCrossRefGoogle Scholar
  25. 25.
    Hess, M.L. and Manson, N.H. J. Mol. Cell Cardiol. 16: 969–985 (1984).PubMedCrossRefGoogle Scholar
  26. 26.
    Nayler, W.G. Am. J. Path. 102: 262–270 (1981).PubMedCentralPubMedGoogle Scholar
  27. 27.
    Coker, S.J., Parratt, S.J., Ledingham, I.M. and Zeitlin, I.J. Nature 29: 323–324 (1981).CrossRefGoogle Scholar
  28. 28.
    Das, U.N. IRCS Med. Sci. BIBR Compend. 9: 385–387 (1981).Google Scholar
  29. 29.
    Hsueh, W. and Needleman, P. Prostaglandins 16: 661–681 (1978).CrossRefGoogle Scholar
  30. 30.
    Blackwell, G.J., Flower, R.J. Br. Med. Bull. 39: 260–264 (1983).PubMedGoogle Scholar
  31. 31.
    Wolf, R.A. and Gross, R.W. J. Biol. Chem. 260: 7295–7303 (1985).PubMedGoogle Scholar
  32. 32.
    Reimersma, R.A. In: Early arrhythmias resulting from myocardial ischaemia (Parratt, J.R. ed.), pp 125–38, Macmillan, London (1982).Google Scholar
  33. 33.
    Schomig, A., Dart, D.M., Dietz, R., Mayer, E. and Kubier, W. Circ. Res. 55: 689–701 (1984).PubMedCrossRefGoogle Scholar
  34. 34.
    Mullane, K.M., Read, N., Salmon, J.A. and Moncada, S. J. Pharmacol. Exp. Ther. 228: 510–522 (1984).PubMedGoogle Scholar
  35. 35.
    Romson, J.L., Hook, B.G., Kunkel, S.L., Abrams, G.R., Schork, M.A. and Lucchesi, B.R. Circulation 62: 1016–1023 (1983).CrossRefGoogle Scholar
  36. 36.
    Dahlgen, M., Peterson, A.L., Engler, R.L. and Schmid-Schonbein, G.W.Google Scholar
  37. 37.
    Engler, R.L., Schmid-Schonbein, G.W. and Pavelec, R.S. Am. J. Pathol, 111: 98–111 (1983).PubMedCentralPubMedGoogle Scholar
  38. 38.
    Bernier, M., Hearse, D.J. and Manning, A.S. Circ. Res. 58: 331–340 (1986).PubMedCrossRefGoogle Scholar
  39. 39.
    Riva, E., Hearse, D.J. and Manning, A.S. J. Mol. Cell. Cardiol. 18: Suppl. 1: (1986).Google Scholar
  40. 40.
    Crome, R., Manning, A.S. Brit. J. Pharmac. Suppl. 1 (1986).Google Scholar
  41. 41.
    Meerson, F.Z., Belkina, L.M. Bioll. Eksp. Biol. Med. 101: 662–664 (1986).Google Scholar
  42. 42.
    Woodward, B., Manning, A.S. In: Life-Threatening Arrhythmias During Ischaemia and Infarction (Hearse, D.J., Manning, A.S. and Janse, M.J. eds.), Raven Press (1986).Google Scholar
  43. 43.
    Hatori, N., Miyazaki, A., Drury, J.K., Moll, J., Rajagopalan, R., Fishbein, M.C., Meerbaum, S. and Corday, E. Circulation 74: Suppl. II: II-346 (1986).Google Scholar
  44. 44.
    Tosaki, A. and Hearse, D.J. Circulation 74: II-254 (1986).Google Scholar
  45. 45.
    Parratt, J.R. and Wainwright, C.L. Br. J. Pharmac. 91: 49–59 (1987).CrossRefGoogle Scholar
  46. 46.
    Manning, A.S. J. Mol. Cell. Cardiol. 18. (Suppl. 1): 197 (abstract) (1986).Google Scholar
  47. 47.
    Barrington, P.L., Meier, C.F., Dickens, B.F. and Weglicki, W.B. Circulation 72 (Suppl. III): 228 (1985).Google Scholar
  48. 48.
    Roy, R.S. and McCord, J.M. In: Radicals and Their Scavenger Systems (Greenwald, R.A. and Cohen, G., eds.), pp 145–153, Elsevier Science, Amsterdam (1983).Google Scholar
  49. 49.
    Manning, A.S., Coltart, D.J. and Hearse, D.J. Circ. Res. 55: 545–548 (1984).PubMedCrossRefGoogle Scholar
  50. 50.
    Manning, A.S., Bernier, M. and Crome, R. J. Mol. Cell. Cardiol, (in press 1987).Google Scholar
  51. 51.
    De Wall, R.A., Vasko, K.A., Stanley, F.L. and Kenzdi, P. Am. Heart J. 82: 362–370 (1971).CrossRefGoogle Scholar
  52. 52.
    Allan, G., Longridge, D.J. Br. J. Pharmacol. 90: 22P (1987).Google Scholar
  53. 53.
    Eaton, E., Peterson, D., Elsperger, J., Asinger, R. and Homans, D. Fed. Proc. 44: 1275 (Abstract) (1985).Google Scholar
  54. 54.
    Downey, J., Chambers, D., Miura, T., Yellon, D. and Jones, D. Circulation 74: Suppl. II: II-372 (1986).Google Scholar
  55. 55.
    Podzuweit, T., Braun, W., Müller, A. and Schaper, W. Circulation 74: Suppl. II: II-346 (1986).Google Scholar
  56. 56.
    Corr, P.B. and Witkowski, F.X. Circulation 68: (Suppl. 1) 16–24 (1983).Google Scholar
  57. 57.
    Coker, S.J., Parratt, J.R., Ledingham, I., Zeitlin, I.J. J. Mol. Cell. Cardiol. 14: 483–485 (1982).PubMedCrossRefGoogle Scholar
  58. 58.
    Coker, S.J. and Parratt, J.R. J. Mol. Cell. Cardiol. 16: 43–52 (1984).PubMedCrossRefGoogle Scholar
  59. 59.
    Mullane, K., Fornabio, D. and Smith, B. Circulation 74: (Suppl. II) II-373 (1986).Google Scholar

Copyright information

© Kluwer Academic Publishers 1988

Authors and Affiliations

  • Allan S. Manning
    • 1
  • Renata Crome
    • 1
  1. 1.Department of BiologyRoche Products LtdWelwyn Garden City, HertsEngland

Personalised recommendations