Abstract
Interferons were originally described as antivirals. Over the years, it has become clear that interferons have additional activities, inclduing modulation of host immune responses. As a result of these additional activities, the possibility exists that interferons could play some role in regulation of host resistance to various non-viral infections. Evidence will be discussed suggesting that interferons are induced during the course of several different types of parasitic infections of mammalian hosts. In addition, evidence obtained from in vitro and in vivo experiments will be presented to indicate that interferons could contribute to resistance of hosts to various parasitic infections. The potential for use of interferons in therapy of parasitic diseases will also be discussed.
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Sonnenfeld, G. (1988). The Promise of Interferon Therapy for Parasitic Diseases. In: Revel, M. (eds) Clinical Aspects of Interferons. Developments in Medical Virology, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1737-1_7
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DOI: https://doi.org/10.1007/978-1-4613-1737-1_7
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