Abstract
Thirty years have elapsed since the discovery of interferon (IFN) as a naturally occurring biological substance with antiviral activity against a broad spectrum of RNA and DNA viruses, but reports of its use in clinical trials of acute viral infections have been surprisingly meager. There are several reasons for this, the major one being that for the first 20 years after its discovery, stocks were in very short supply, and when available, very expensive.
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Keywords
- Human Papilloma Virus
- Herpes Zoster
- Acquire Immune Deficiency Syndrome
- Genital Herpes
- Japanese Encephalitis
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References
Levin, S. and Hahn, T. Clin. exp. Immunol. 60:267–73, 1985.
Levin, S. and Hahn, T. Clin. exp. Immunol. 46:475–83, 1981.
Levin, S. and Hahn, T. Lancet i:592–4, 1982
Shanon, A. and Levin, S. Pediatric Rev. Commun. 1:-, 1987.
Shalev, Y., Berrebi, A., Green, L., Levin, S. et al. Arch. Dermatol. 120:922–929, 1984.
Levin, S. J. Infect. Dis. 151:745–6, 1985
Roisman, B. and Batterson, W. In: Virology (Ed. B.N. Fields), Raven Press. N.Y., 1985, p 497.
Isaacson, M., Berson, B., Steinberg, J. and Morag, A. Isr. J. Med. Sci. 19:959–962, 1983.
Ikic, D., Trajer, D., Cupak, K. et al. J. Clin. Pharmacol. Ther. and Toxicol. 19:498–505, 1981.
Jones, B.R. In: Herpetic eye diseases (Ed. R. Sundmacher), Bergman, Munich, 1981, pp. 395–400.
Mecere, P.J. and Van Bujsterveld, O.R. Antiviral Res. 1:225–228, 1985.
De Koning, E.W.J., Van Bijsterveld, O.R. and Cantell, K. Arch. Opthalmol. 101:1866–1868, 1983.
Sundmacher, R., Cantell, K. and Mattes, A. Arch-Opthalmol. 102:554–555, 1984.
De Koning, E.W.J., Van Bijsterveld, O.R. and Cantell, K. Brit. J. Opthalmol. 66:509–512, 1982.
De La Pena, N.C., Diaz, A., Darnel, A. et al. Biomedicine 28: 104–108, 1978.
Clercg, E.de, Edy, V.G. and Vlieger, H.de. J. Pediatr. 86:736–739, 1975.
Pazin, G.J., Armstrong, J.A. et al. N. Engl. J. Med. 301:225–230, 1979.
Cheesman, S.H., Rubin, R.H., Stewart, J.A. et al. N. Engl. J. Med. 300:1345–1349, 1979.
Merigan, T.C., Rand, R.H., Polard, R.B. et al. N. Engl. J. Med. 298:981–987, 1978.
Arum, A.M. Kushner, J.H., Feldman, S. et al. N. Engl. J. Med. 306:761–765, 1982.
Shepp, D.H., Dandliker, P.S. and Meyers, J.D. N. Engl. J. Med. 314:208–212, 1986.
Cheeseman, S.H., Henle, W., Rubin, R.H. et al. Ann. Intern. Med. 93:39–42, 1980.
Treuner, J. and Niethammer, D. In: Interferon 4: In vivo and clinical studies. (Eds. N.B. Finter and R.K. Oldham). Elsevier, Amsterdam, 1985, pp. 280–295.
Krugman, S. In: Infectious disease of children, 8th Edit. (Eds: S. Krugman, S. Katz, A.A. Gershon and C.M. Wilfert), Mosby Co, St. Louis, 1985, pp. 8–21.
Hirsch, M.S., Schooley, R.T. et al. N. Engl. J. Med. 308:1489–1493, 1983.
Wade, J.C., McGuffin, S.C. et al. Jnl. Infect. Dis. 148:557–562, 1983.
Hayden, F.G., Albrecht, J.K., Kaiser, D.L., Gwaltney, J.M. N. Engl. J. Med. 314:71–75, 1986.
Hayden, F.G., and Gwaltney, J.M. J. Infect. Dis. 150:174–188, 1984.
Douglas, R.M., Moore, B.W. et al. N. Engl. J. Med. 314:65–70, 1986.
Philpotts, R.J., Higgins, P.J. et al. Jnl. Interferon Res. 4: 535–541, 1984.
Leventhal, Kashima, H., Wishnant, J.K. and Tuttle, R. In: Interferon 4: In vivo and clinical studies. (Eds. NB Fintner and RK Oldham), Elsevier, Amsterdam, 1985, pp. 325–334.
Sessions, R.B., Dichtel, W.J. and Goepfert, H. ENT Journal, 63: 488–493, 1984.
Geffen, J.R., Klein, R.J., Friedman-Kien, A.E. J. Infect. Dis. 180:612–615, 1984.
Gall, S.A., Hughes, C.E. and Trofatter, R. Am.J. Obstet. Gynecol. 153:157–163, 1985.
Schonfeld, A., Schattner, A. et al. Lancet i:1038–1042, 1984.
Bye, A., Balkwill, F., Brigden, D., Wilson, J. Develop. Med. Child. Neurol. 27:170–175, 1985.
Mizutani, N., Miyazu, M. et al. Tohoku J. Exp. Med. 146:277–284, 1985.
Nakagawa, M., Michihata, T. et al. Acta Paediatr. Scand. 74:309–310, 1985.
Merigan, T.C., Beer, G.M., Winkler, W.G. et al. Ann. Neurol. 16: 82–87, 1984.
Levin, S., Hahn, T., Handzel, Z.T. et al. Antiviral Res. 5:229–240, 1985.
Larsson, A., Forsgren, M. et al. Acta Paediatr. Scand. 65:105–110, 1976.
Yoon, J.W., Auskin, M., Onodera, T., Notkins, A.L. N. Engl. J. Med. 300:1173–1179, 1979.
Zadik, Z., Levin, S. and Handzel, Z.T. J. Pediatr. Endocrinol. 1:119–122, 1985.
Rand, K.H., Rosenblood, A.L. et al. Diabetologia. 21:16–19, 1982.
Emond, R.T.D., Evans, B., Boven, E.T.W., and Lloyd, G. BMJ. 2: 541–544, 1977.
Ben Moshe, H., Romano, A., Blumenthal, M. and Revel, M. Metabol. Pediatr. Ophthalmol. 5:191–193, 1981.
Milazzo, F., Galli, M., Fassio, P.G. Infections. 13:130–133, 1985.
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© 1988 Kluwer Academic Publishers, Boston
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Levin, S., Leibowitz, E. (1988). Interferon Therapy in Acute Viral Illnesses. In: Revel, M. (eds) Clinical Aspects of Interferons. Developments in Medical Virology, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1737-1_3
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DOI: https://doi.org/10.1007/978-1-4613-1737-1_3
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