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Pharmacokinetics of Interferons and Practical Implications

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Clinical Aspects of Interferons

Part of the book series: Developments in Medical Virology ((DIMV,volume 4))

Abstract

The pharmacokinetics of IFN’s α, β and γ are reviewed pointing out their short half-lives, their distribution and major catabolic sites. After several years of IFN clinical trials based on empirical approaches it is now clear that IFNs are pharmacodynamically neither comparable to antibiotics nor to cytotoxic agents and it may be useful to test unconventional routes of administration which may improve their therapeutic index.

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Author information

Authors and Affiliations

  1. Institute of General Physiology, University of Siena, Via Laterina 8, 53100, Siena, Italy

    V. Bocci

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  1. V. Bocci
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Editor information

Editors and Affiliations

  1. The Weizmann Institute of Science, Israel

    Michel Revel

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© 1988 Kluwer Academic Publishers, Boston

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Bocci, V. (1988). Pharmacokinetics of Interferons and Practical Implications. In: Revel, M. (eds) Clinical Aspects of Interferons. Developments in Medical Virology, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1737-1_20

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  • DOI: https://doi.org/10.1007/978-1-4613-1737-1_20

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8977-7

  • Online ISBN: 978-1-4613-1737-1

  • eBook Packages: Springer Book Archive

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