Abstract
Human osteosarcoma is a malignant disease which requires multi-modality treatment including surgery and adjuvant therapy. In this article we have summarized various aspects pertinent to IFN therapy of human osteosarcoma. Different experimental approaches are described but we emphasize that IFN treatment should not be used as the primary single treatment in osteosarcoma. Osteosarcoma exerts biological effects which makes it possible to study biological parameters extensively. Such a biological approach might lead to an extensive combination treatment schedule and a diversified programme for the treatment of human osteosarcoma patients.
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Strander, H. et al. (1988). Osteosarcoma Management and Interferon. In: Revel, M. (eds) Clinical Aspects of Interferons. Developments in Medical Virology, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1737-1_14
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