Abstract
Since 1981, we have conducted a series of clinical trials with interferons for the treatment of Philadelphia chromosome-positive chronic myelogenous leukemia (CML Ph’). The interferons examined are partially pure alpha interferon, followed by recombinant alpha A interferon (Roche), recombinant gamma interferon, and most recently, combinations of alpha and gamma interferons. Here we summarize what we consider to be the major concepts emerging from those trials.
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© 1988 Kluwer Academic Publishers, Boston
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Talpaz, M., Kurzrock, R., Kantarjian, H., Gutterman, J.U. (1988). Clinical Studies of Alpha and Gamma Interferons in Chronic Myelogenous Leukemia. In: Revel, M. (eds) Clinical Aspects of Interferons. Developments in Medical Virology, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1737-1_10
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DOI: https://doi.org/10.1007/978-1-4613-1737-1_10
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