Natural History of Aortic Regurgitation

  • Charles R. McKay
  • Shahbudin H. Rahimtoola
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 85)

Abstract

Aortic regurgitation was described by Cowper in 1705, who noted progressive heart failure associated with calcified insufficient aortic valves and very large hearts [1]. The clinical findings of increased pulse pressure with rapid diastolic collapse were associated with aortic valve incompetence by Corrigan in 1832 [2]. Austin Flint described the associated functional mitral middiastolic and presystolic murmurs in 1870 and noted that medical treatment with digitalis and diuretics could be helpful in these patients [3], Seventy-four years later, White [4] noted that once overt heart failure occurred, the prognosis was poor despite medical treatment with these same drugs. Hufnagel described the first “direct” mechanical treatment of aortic insufficiency by placing a ball valve prosthesis in the descending aorta [5]. It remained for Harken [6] and Lillehei [7] to actually replace the incompetent aortic valve with prosthetic devices. Aortic valve replacement with prosthetic valves has dramatically improved the clinical status of these patients[8].

Keywords

Arthritis Arsenic Radionuclide Cardiol Perforation 

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Copyright information

© Kluwer Academic Publishers 1988

Authors and Affiliations

  • Charles R. McKay
  • Shahbudin H. Rahimtoola

There are no affiliations available

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