Abstract
Solar ultraviolet radiation (UV) is a ubiquitous environmental agent known to produce numerous effects in human skin. These effects Include inflammation, pigmentation, carcinogenesis, local and systemic immune suppression, aging and Vitamin D metabolism. In addition, such radiation can produce cutaneous disease in individuals rendered abnormally photosensitive by the presence of exogenous drugs and chemicals or endogenous substances such as porphyrins. The mechanisms by which such radiation evokes most of these cutaneous photobiological effects have been studied in some detail but the responses remain poorly understood.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Cavallo, J. and DeLeo, V.A. Derm. Clinics 4:181–188, 1986.
Epstein, J.H., Fukuyama, K. and Fye, K. Photochem. Photobiol. 12:57–65, 1970.
Lowe, N.J. and Stoughton, R.B. J. Invest. Dermatol. 68:134–137, 1977.
Rundel, R.D. Photochem. Photobiol. 38:569–575, 1983.
Staberg, B., Wulf, H.C., Paulsen, T., Klemp, P. and Brodthagen, H. Arch. Dermatol. 119:641, 1983.
Wilis, I., Menter, J.M. and Whyte, J.H. J. Invest. Dermatol. 76:404–408, 1981.
Weinstein, I.B., Mufson, R.A., Lih-Syng, L., Fisher, P.B., Laskin, J., Horowitz, A.D. and Ivanovic, U. In: Carcinogenesis: Fundamental Mechanisms and Environmental Effects (Ed. P.B. Reidel), W.B. Saunders, New York, 1980, pp. 543–563.
Nondlund, J.J. and Ackles, E.E. Biological Molecular and Clinical Aspects of Pigmentation, University of Tokyo Press, Tokyo, 1985, pp. 501–513.
Nondlund, J.J., Collins, CE. and Rheins, L.A. J. Invest. Dermatol. 86:433–437, 1986.
DeLeo, V.A., Hanson, D., Weinstein, I.B. and Harber, L.C. Photochem. Photobiol. 41:51–56, 1985.
DeLeo, V.A., Miller, S., Chew, S. and Scheide, S. Photochem. Photobiol. 43:92S, 1986.
DeLeo, V.A., Hanson, D. and Scheide, S. Tox. Letters 32:215–220, 1986.
Gilchrest, B.A., Soter, N.A., Stoff, J.S. and Mihm, M.C. J. Am. Acad. Dermatol. 5:411–422, 1981.
Keahey, T.M., Wehsen, G.F., Kaidbey, K.H. and Lauker, K.M. J. Invest. Dermatol. 78:355, 1982.
Lim, H.W., Panker, D. and Marcus, A.J. Clin. Res. 34:763A, 1986.
Hardcastle, J.E. and Minoui, S. Manuscript in preparation.
DeLeo, V.A., Horlick, H., Hanson, D., Eisinger, M. and Harber, L.C. J. Invest. Dermatol. 83:323–326, 1984.
Punnonen, K., Puustinen, T. and Jansen, C.T. Arch. Dermatol. 278:441–444, 1986.
Punnonen, K., Puustinen, T. and Jansen, C.T. Photochem. Photobiol. 44:623–627, 1986.
Karmali, R.A. and Safai, B. Prostagladins Leukotrienes and Med. 15:277–286, 1984.
Moller, A., Schwanitz, H.J. and Czarnetzki, B.M. J. Invest. Dermatol. 87:489–493, 1986.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1988 Kluwer Academic Publishers, Boston
About this chapter
Cite this chapter
Deleo, V. (1988). Effect of Ultraviolet Radiation on Eicosanoid Metabolism of Cells in Culture. In: Polgar, P. (eds) Eicosanoids and Radiation. Prostaglandins, Leukotrienes, and Cancer, vol 5. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1723-4_5
Download citation
DOI: https://doi.org/10.1007/978-1-4613-1723-4_5
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-8970-8
Online ISBN: 978-1-4613-1723-4
eBook Packages: Springer Book Archive