Abstract
In recent years, the possible role(s) of excitatory amino acid (EAA) transmitters in neuropsychiatric disorders has become a topic of considerable interest. Two rather dissimilar hypotheses have evolved: 1) that excess EAA receptor stimulation might be the mechanism underlying certain neurodegenerative disorders; 2) that insufficient EAA receptor stimulation may lead to psychotic processes and/or memory dysfunction. Here evidence relevant to each of these hypotheses will be discussed.
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Supported in part by NIMH Research Scientist Award (MH 38894) and a grant from the Washington University/Monsanto Biomedical Research Fund.
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© 1988 Kluwer Academic Publishers
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Olney, J.W. (1988). Excitatory Transmitters and Neuropsychiatry Disorders. In: Ferrendelli, J.A., Collins, R.C., Johnson, E.M. (eds) Neurobiology of Amino Acids, Peptides and Trophic Factors. Topics in the Neurosciences, vol 8. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1721-0_4
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DOI: https://doi.org/10.1007/978-1-4613-1721-0_4
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