Abstract
Recent studies have shown that blockade of GABA in the posterior hypothalamic nucleus of rats elicits increases in heart rate, respiratory rate, and, to a lesser extent, arterial pressure [1, 2]. These autonomic changes are similar to those seen in emotional defense reactions in conscious rats [3]. The present study was aimed at testing the hypothesis that GABA blockade in this cardio-stimulatory area of the posterior hypothalamus in conscious animals would elicit aversively motivated behaviors.
Keywords
- Approach Schedule
- Lateral Hypothalamic Area
- Posterior Hypothalamus
- Locomotor Stimulation
- Avoidance Schedule
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Supported by grants USPHS NS 19883 and PHS MH 17107, NIMH.
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© 1988 Kluwer Academic Publishers
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Shekhar, A., Hingtgen, J.N., Dimicco, J.A. (1988). Role of Hypothalamic Gaba in Aversively Motivated Behaviors. In: Ferrendelli, J.A., Collins, R.C., Johnson, E.M. (eds) Neurobiology of Amino Acids, Peptides and Trophic Factors. Topics in the Neurosciences, vol 8. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1721-0_24
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DOI: https://doi.org/10.1007/978-1-4613-1721-0_24
Publisher Name: Springer, Boston, MA
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