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Organometallic Titanocene and Ferricenium Complexes: Antitumor and Toxicologic Properties

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Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy

Part of the book series: Developments in Oncology ((DION,volume 54))

Abstract

Following the detection and clinical approval of cytostatic platinum complexes, antitumor activity was revealed during the past years for numerous other quite different inorganic and organometallic compounds. Metallocene and metalliceniurn complexes represent examples of organometallic compounds containing early or medium transition metals. Their antiproliferative activity has been detected in 1979 and 1984, respectively (1–3). Together with copper and gold complexes (4,5) and main group element compounds (6–9), metallocene and metallicenium complexes belong to the class of non-platinum group metal antitumor agents (10).

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© 1988 Martinus Nijhoff Publishing, Boston

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Köpf-Maier, P. (1988). Organometallic Titanocene and Ferricenium Complexes: Antitumor and Toxicologic Properties. In: Nicolini, M. (eds) Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy. Developments in Oncology, vol 54. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1717-3_66

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  • DOI: https://doi.org/10.1007/978-1-4613-1717-3_66

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8967-8

  • Online ISBN: 978-1-4613-1717-3

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