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Effect of Cis-Diamminedichloroplatinum(II) on the Nucleotide Pool of Treated P388 Leukemia Cells

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Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy

Part of the book series: Developments in Oncology ((DION,volume 54))

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Abstract

The Effect of cis-diamminedichloroplatinum(II) (cisDDP)-complexes on the regulatory state of P388 mouse leukemia cells has first been investigated preliminary on Ap4A, a supposed cell growth effector (1), known already for forming a defined and non-metabolizable chelate with either cis- and trans- DDP (cis-, trans-Pt-Ap4A)(2).

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© 1988 Martinus Nijhoff Publishing, Boston

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Just, G., Holler, E. (1988). Effect of Cis-Diamminedichloroplatinum(II) on the Nucleotide Pool of Treated P388 Leukemia Cells. In: Nicolini, M. (eds) Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy. Developments in Oncology, vol 54. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1717-3_10

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  • DOI: https://doi.org/10.1007/978-1-4613-1717-3_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8967-8

  • Online ISBN: 978-1-4613-1717-3

  • eBook Packages: Springer Book Archive

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