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Mumps Virus: Molecular Aspects and Its Effects on the Central Nervous System

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Clinical and Molecular Aspects of Neurotropic Virus Infection

Part of the book series: Developments in Medical Virology ((DIMV,volume 5))

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Abstract

Mumps virus normally causes a benign childhood illness characterized by mild morbidity and rare mortality. One of the most striking properties of this virus is its ability to infect the human central nervous system (CNS). Mumps was reported as the virus most commonly associated with meningitis and encephalitis (66) with as many as 50% of studied patients showing evidence of meningeal involvement (2). The development of an effective vaccine has lessened the impact of mumps in the United States. However, worldwide, mumps remains an important human pathogen with potentially life-threatening CNS complications.

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  1. Department of Neurology, The University of Texas Health Science Center at Houston, Houston, Texas, 77225, USA

    M. Neal Waxham Ph.D.

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Editors and Affiliations

  1. Department of Neurology, University of Colorado Health Sciences Center, Denver, CO, 80262, USA

    Donald H. Gilden M.D. (Professor and Chairman) (Professor and Chairman)

  2. Department of Neurology, Northwestern University Medical School, Chicago, Illinois, 60611, USA

    Howard L. Lipton M.D. (Professor and Acting Chairman) (Professor and Acting Chairman)

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Waxham, M.N. (1989). Mumps Virus: Molecular Aspects and Its Effects on the Central Nervous System. In: Gilden, D.H., Lipton, H.L. (eds) Clinical and Molecular Aspects of Neurotropic Virus Infection. Developments in Medical Virology, vol 5. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1675-6_8

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