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A Randomized Prospective Evaluation of Leuprolide versus Diethylstilbestrol in the Treatment of Stage D2 Metastatic Prostate Cancer: Results of a Multicenter Study

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Abstract

For the past 40 years since the observation by Huggins and Hodges that surgical castration or diethylstilbestrol (DES) could bring relief of symptoms from metastatic prostate cancer, these have been the standard therapies for the initial treatment of that disease (1,2). However, during that time the search for less toxic and more acceptable forms of therapy has continued.

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© 1988 Plenum Press, New York

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Garnick, M.B., Swanson, L.J., Max, D.T. (1988). A Randomized Prospective Evaluation of Leuprolide versus Diethylstilbestrol in the Treatment of Stage D2 Metastatic Prostate Cancer: Results of a Multicenter Study. In: Coffey, D.S., Resnick, M.I., Dorr, F.A., Karr, J.P. (eds) A Multidisciplinary Analysis of Controversies in the Management of Prostate Cancer. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1667-1_23

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  • DOI: https://doi.org/10.1007/978-1-4613-1667-1_23

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8925-8

  • Online ISBN: 978-1-4613-1667-1

  • eBook Packages: Springer Book Archive

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