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Chemical and Immunochemical Studies on Lipopolysaccharides of Coxiella Burnetii Phase I and Phase II

  • Hubert Mayer
  • Joanna Radziejewska-Lebrecht
  • Stefan Schramek
Chapter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 228)

Abstract

Coxlella burnetii, etiological agent of both acute and chronic Q-fever, is an obligate intracellular bacterial parasite. It is the only species of the genus Coxiella of the Rickettsiaceae family, and all strains so far studied belong to the same serotype (Bergey’s Manual, 1984).

Keywords

Sugar Composition Coxiella Burnetii Terminal Linkage Alditol Acetate Mouse Spleen Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Amano, K.I., and Williams, J.C. (1984) Chemical and immunological characterization of lipopolysaccharides from phase I and phase II Coxiella burnetii. J. Bacteriol. 160: 994–1002.PubMedGoogle Scholar
  2. 2.
    Amano, K.I., Fukushi, K., and Williams, J. (1985). Chemical and ultrastructural properties of lipopolysaccharides from phase I and phase II. Abstr. 5th Nat. Conf. Am. Soc. Rickettsiology and Rickettsial Diseases. Laguna Beach, CA. March 1–3, 1985.Google Scholar
  3. 3.
    Baca, O.G., Martinez, I.L., Aragón, A.S., and Klassen, D. (1980 Isolation and partial characterization of a lipopolysaccharide from phase II Coxiella burnetii. Can. J. Microbiol., 26:819–826.CrossRefGoogle Scholar
  4. 4.
    Baca, O.G., and Paretsky, D. (1974) Some physiological and biochemical effects of a Coxiella burnetii lipopolysaccharide preparation on guinea pigs. Infect. Immun. 9:939–945.PubMedGoogle Scholar
  5. 5.
    Bergey’s Manual of Systematic Bacteriology. (1984). Vol. 1, pp. 701–704. “Coxiella” by Weiss, E. and Moulder, J.W., Williams and Wilkins, Baltimore, USA.Google Scholar
  6. 6.
    Brezina, R. (1978). Phase variation phenomenon in Coxiella burnetii, in: “Rickettsiae and Rickettsial Diseases” (eds), J. Kazár, R.A. Ormsbee, and I.N. Tarasevich, pp. 221–235, Veda, Bratislava.Google Scholar
  7. 7.
    Dahlman, O., Garegg, P., Mayer, H., and Schramek, S. (1986). Synthesis of three 3-C-hydroxymethylpentoses with the D-ribo, D-xylo and L-lyxo-configurat ions. Identification of the latter with a monosaccharide isolated from phase I Coxiella burnetii lipopolysaccharide. Acta Chem. Scand. Ser. B 40., 15–20.Google Scholar
  8. 8.
    Galanos, C., Liideritz, O., Rietschel, E. Th., and Westphal, O. (1977) Newer aspects of the chemistry and biology of bacterial polysaccharides, with special reference to their lipid A component, in: “International Review of Biochemistry: Biochemistry of lipids II”, vol 14, T.W. Goodswin (eds.), pp. 239–335, University Press, Baltimore.Google Scholar
  9. 9.
    Galanos, C., Freudenberg, M.A., Jay, F., Nerka, D., Veleva, K., Brade, H., and Strittmatter, W. (1984) Immunogenic properties of lipid A. Rev. Infect. Dis. 6: 546–552.PubMedCrossRefGoogle Scholar
  10. 10.
    Hackstadt, T., Peacock, M.G., Hitchcock, P.J., and Cole, R. (1985). Lipopolysaccharide variation in Coxiella burnetii: Intrastrain heterogeneity in structure and antigenicity. Infect. Immun. 48.: 359–365.PubMedGoogle Scholar
  11. 11.
    Kazár, J., Brezina, R., Schramek, S., Urvölgyi, J., Pospisil, V., and Kovácová, E. (1974). Virulence, antigenic properties and physicochemical characteristic of Coxiella burnetii strains with different chick embryo yolk sac passage history. Acta virol., 18.: 434–442.Google Scholar
  12. 12.
    Kulyaeva, V.V., Kudinova, M.K., Potanova, N.P., Rubasheva, L.M., Brazhnikov, M.G., Rozynov, B.V., and Bekker, A.R. (1978). Structure of the carbohydrate moiety of the antibiotic verenomycin. Bioorg. Khim. 1978:1087–1092.Google Scholar
  13. 13.
    Mayer, H., Dahlman, O., Garegg, P.J., Radziejewsk-Lebrecht, J., and Schramek, S. (1985) Lipopolysaccharides of Coxiella burnetii: Identification of virenose and dihydrohydroxystreptose in phase I and the structure of phase II lipopolysaccharide. Glycoconjugates, Proc. VIIIth Intern. Symposium, Houston, Texas, Sep. 8–13, Vol. I, 77–78.Google Scholar
  14. 14.
    Radziejewska-Lebrecht, J., Feige, U., Mayer, H., and Weckesser, J. (1981). Structure of the heptose region of lipopolysaccharides from Rhodospirillum tenue. J. Bact. 145:138–144.PubMedGoogle Scholar
  15. 15.
    Rietschel, E.Th., Galanos, C., Luderitz, O., and Westphal, O. (1982). Chemical structure, physiological function and biological activity of lipopolysaccharides and lipid A, in: “Immunopharmacology and the regulation of leucocyte function”, E.R. Webb (eds), pp. 183–229, M. Dekker, New York.Google Scholar
  16. 16.
    Rietschel, E.Th., Wollenweber, H.W., Russa, R., Brade, H., and Zahringer, U. (1984) Concepts of the chemical structure of lipid A. Rev. Infect. Dis. 6.: 432–438.Google Scholar
  17. 17.
    Schramek, S. (1978). Rickettsial endotoxic lipopolysaccharides, in “Rickettsiae and Rickettsial Diseases”, J. Kazár, R.A. Ormsbee, I.N. Tarasevich (eds.), pp. 79–87, Veda, Bratislava.Google Scholar
  18. 18.
    Schramek, S., and Brezina, R. (1976) Characterization of an endotoxic lipopolysaccharide form Coxiella burnetii, Acta virol. 20.: 152–158.Google Scholar
  19. 19.
    Schramek, S., Brezina, R. (1979). Isolation of endotoxic lipopolysaccharide from Phase II Coxiella burnetii. Acta virol. 23:349.PubMedGoogle Scholar
  20. 20.
    Schramek, S., Brezina, R., and Kazár, J. (1978) Influence of mild acid hydrolysis on the antigenic properties of phase I Coxiella burnetii. Acta virol. 22.: 302–308.Google Scholar
  21. 21.
    Schramek, S., Brezina, R., and Visacka, E. (1983) Different antigenic properties of lipopolysaccharides isolated from Coxiella burnetii in phase I and pure phase II. Zbl. Bakt. Hyg., I Abt. Orig. A, 255:356–360.Google Scholar
  22. 22.
    Schramek, S., and Galanos, C. (1981). Lipid A component of lipopolysaccharides from Coxiella burnetii. Acta Virol 25:230–234.PubMedGoogle Scholar
  23. 23.
    Schramek, S., and Mayer, H. (1982). Different sugar composition of lipopolysaccharides isolated from phase I and pure phase II cells of Coxiella burnetii. Infect. Immun. 38:53–57.PubMedGoogle Scholar
  24. 24.
    Schramek, S., Radziejewska-Lebrecht, J., and Mayer, H. (1985). 3-C-branched aldoses in lipopolysaccharide of phase I Coxiella burnetii and their role as immunodominant factors, Eur. J. Biochem., 148.: 445–461.CrossRefGoogle Scholar
  25. 25.
    Shiba, T. and Kusumoto, S. (1984). “Chemical Synthesis and biological activity of lipid A analogs”. In: Handbook of Endotoxin, Vol. I: Chemistry of Endotoxin, E. Rietschel (ed.), Elsevier, Amsterdam and New York.Google Scholar
  26. 26.
    Stodola, F.H., Shotwell, O.L., Borud, A.M., Benedict, R.G., and Riley, A.C. Jr. (1951) Hydroxystreptomycin, a new antibiotic from Streptomyces griseocarneus. J. Am. Chem. Soc. 73:2290–2293.CrossRefGoogle Scholar
  27. 27.
    Visacká, E., Schramek, S., Kazár, J., Kovácová, E., and Brezina, R. (1984) Changing of antigenic, immunogenic and chemical properties of a Coxiella burnetii strain during chick embryo yolk sac passaging. Acta virol. 28:300–308.PubMedGoogle Scholar
  28. 28.
    Weiss, U., Yoshihira, K., Highet, R.G., White, R.J., and Wei, T.Z. (1982) The chemistry of the antibiotics chrysomycin A and B. Antitumor activity of chryso-mycin. A.J. Antibiot. (Tokyo) 35.: 1194–1201.Google Scholar
  29. 29.
    Wollenweber, H.W., Schramek, S., Moll, H., and Rietschel, E.T. (1985) Nature and linkage type of fatty acids present in lipopolysaccharides of phase I and phase II Coxiella burnetii. Arch. Microbiol., 142:6–11.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Hubert Mayer
    • 1
  • Joanna Radziejewska-Lebrecht
    • 2
  • Stefan Schramek
    • 3
  1. 1.Max-Planck-Institut für ImmunbiologieFreiburg i.BrGermany
  2. 2.Institute of MicrobiologyUniversity of LódźPoland
  3. 3.Institute of VirologySlovak Academy of SciencesBratislavaCSSR

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