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Carbohydrate Structures as ONCO-Developmental Antigens and Components of Receptor Systems

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The Molecular Immunology of Complex Carbohydrates

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 228))

Abstract

In this article I shall review our research activities which have been focused on the antigenicities and biological roles of carbohydrate structures of glycoproteins and glycolipids. I shall first discuss examples of carbohydrate structures which behave as onco-developmental antigens recognized by monoclonal antibodies. This will be followed by a discussion of the possible involvement of carbohydrates in the functions of growth factor receptors and in the interactions of embryonic cells. The last section will be concerned with observations on the carbohydrate receptors for an infective agent, Mycoplasma pneumoniae, and new clues to the triggering of autoantibodies following human infection with this agent.

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Authors and Affiliations

  1. Applied Immunochemistry Research Group, Clinical Research Centre, Watford Road, HA1 3UJ, Harrow, Middlesex, UK

    Ten Feizi

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  1. Ten Feizi
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Editors and Affiliations

  1. Texas Agricultural Experimental Station, Texas A&M University, College Station, Texas, USA

    Albert M. Wu  & L. Garry Adams  & 

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© 1988 Plenum Press, New York

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Feizi, T. (1988). Carbohydrate Structures as ONCO-Developmental Antigens and Components of Receptor Systems. In: Wu, A.M., Adams, L.G. (eds) The Molecular Immunology of Complex Carbohydrates. Advances in Experimental Medicine and Biology, vol 228. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1663-3_11

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  • DOI: https://doi.org/10.1007/978-1-4613-1663-3_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8923-4

  • Online ISBN: 978-1-4613-1663-3

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